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Cannabinoid Receptor Agonist

Opioid Use Disorder for Opioid Use Disorder

Phase 1
Recruiting
Led By Anahita Bassir Nia, MD
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up one time within 4 weeks of screening
Awards & highlights

Summary

The goal of this research study is to examine the endocannabinoid (eCB) function in vivo in individuals with opioid use disorder (OUD) by measuring cannabinoid receptor 1 (CB1R) availability.

Eligible Conditions
  • Opioid Use Disorder
  • Healthy Controls

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~one time within 4 weeks of screening
This trial's timeline: 3 weeks for screening, Varies for treatment, and one time within 4 weeks of screening for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
CB1R Availability
Secondary study objectives
Serum Endocannabinoid Levels

Trial Design

2Treatment groups
Experimental Treatment
Group I: Opioid Use DisorderExperimental Treatment1 Intervention
Patients diagnosed with opioid use disorder
Group II: Healthy VolunteersExperimental Treatment1 Intervention
Healthy volunteers with no current or past major medical or psychiatric history

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,543 Previous Clinical Trials
3,249,346 Total Patients Enrolled
Yale UniversityLead Sponsor
1,907 Previous Clinical Trials
3,019,019 Total Patients Enrolled
Anahita Bassir Nia, MDPrincipal InvestigatorYale University
2 Previous Clinical Trials
78 Total Patients Enrolled
~13 spots leftby Dec 2025