Strengthening Exercises for Thumb Osteoarthritis

N/A

Recruiting

Led By Neal Chen, MD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at enrollment and 12 week follow up

Summary

This trial looks at whether strengthening the first dorsal interosseus muscle helps reduce pain and thumb disability in patients with thumb CMC osteoarthritis.

Who is the study for?

This trial is for English-speaking adults over 18 with thumb carpometacarpal (CMC) osteoarthritis who have been treated with a splint. It's not for those who've had corticosteroid injections for CMC osteoarthritis or have rheumatoid arthritis or post-traumatic CMC osteoarthritis.

What is being tested?

The study aims to see if strengthening the first dorsal interosseous (FDI) muscle helps people with thumb CMC osteoarthritis. Participants will either use a splint alone or combine it with specific strengthening exercises.

What are the potential side effects?

While there are no major side effects expected from using a splint or doing strengthening exercises, some participants might experience discomfort or strain in their hands during the exercise regimen.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at enrollment and 12 week follow up

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at enrollment and 12 week follow up

This trial's timeline: 3 weeks for screening, Varies for treatment, and at enrollment and 12 week follow up for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity Computer Adaptive Test (CAT) at 12 weeks

Difference in 3-point chuck strength at 12 weeks

Difference in Lateral pinch strength at 12 weeks

+1 more

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Splint with first dorsal interosseous (FDI) strengtheningActive Control1 Intervention

Subjects with carpometacarpal (CMC) osteoarthritis treated by splinting of their thumb combined with first dorsal interosseous (FDI) strengthening stabilization exercises.

Group II: Splint OnlyPlacebo Group1 Intervention

Subjects with carpometacarpal (CMC) osteoarthritis treated by splinting of their thumb.

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