Web-Based Lifestyle Interventions for Cancer Survivor Health
(AMPLIFY Trial)

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byWendy Demark-Wahnefried, PhD, RD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Alabama at Birmingham

No Placebo Group

Trial Summary

What is the purpose of this trial?This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial, renal, thyroid, and ovarian cancers, as well as multiple myeloma and non-Hodgkin Lymphoma. Overarching outcomes also include physical function and performance, muscle mass, quality of life, and health utilities.

Eligibility Criteria

This trial is for early-stage cancer survivors over 50, living in the US with a BMI of 25-50 kg/m2 and less than 150 minutes of exercise per week. They must have finished primary treatment, not be in another diet-exercise program, or have progressive/recurrent cancer. Those with severe health conditions that limit physical activity are excluded.

Inclusion Criteria

You are able to read and write English.\n

I have finished my main cancer treatment or am on active surveillance for prostate cancer or ductal carcinoma in situ.

Reside in an area that receives wireless coverage

+15 more

Exclusion Criteria

I do not have any health conditions that would stop me from following a weight loss plan on my own.

My cancer has come back, but it's not just a rise in prostate cancer markers.

Reside in a skilled nursing or assisted living facility

+4 more

Participant Groups

The AMPLIFI Cancer Survivor Health study tests web-based interventions to improve diet and exercise among survivors of various cancers. It aims to see if these programs can enhance physical function, muscle mass, quality of life, and overall health.

3Treatment groups

Experimental Treatment

Group I: Project 3: Combined Diet and ExerciseExperimental Treatment3 Interventions

Participants will receive the diet and exercise content simultaneously in combined web-based sessions. Participants will receive and participate in web-based sessions that focus on diet and exercise for 12 months. Participants will be encouraged to track their diet, weight and physical activity data (minutes and step counts). Tailored feedback and goal recommendations will be provided through the website. Participants will also receive access to resources for relevant behavioral topics. All participants will be invited to participate in the secret Facebook group for the project (though participation is optional).

Group II: Project 2: Exercise-DietExperimental Treatment2 Interventions

Participants will receive and participate in web-based sessions that focus on diet for 6 months, followed by exercise for another 6 months. Participants will be encouraged to track their diet and weight for the first 6 months and to log their data in the intervention website, during the second 6 months they will be asked to log their physical activity data (minutes and step counts). Tailored feedback and goal recommendations will be provided through the website. Participants will also receive access to resources for relevant behavioral topics. All participants will be invited to participate in the secret Facebook group for the project (though participation is optional).

Group III: Project 1: Diet-ExerciseExperimental Treatment2 Interventions