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Home-Based Exercise for Cancer Patients

N/A

Recruiting

Led By Christina Dieli-Conwright, PhD, MPH

Research Sponsored by Dana-Farber Cancer Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Newly diagnosed with stage I-III breast, colorectal or prostate cancer

Over 18 years old; children under the age of 18 will be excluded due to rarity of disease

Must not have

Patients should not have any uncontrolled illness including ongoing or active infection, uncontrolled diabetes, hypertension, or thyroid disease

Patients with metastatic disease

Timeline

Screening 3 weeks

Treatment Varies

Follow Up evaluated at months 2 and 4

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether a 16-week, home-based, aerobic and resistance exercise intervention will increase physical activity levels in Black and Hispanic breast, colorectal, or prostate cancer patients.

Who is the study for?

This trial is for Black and Hispanic adults over 18 with stage I-III breast, colorectal, or prostate cancer who are overweight/obese. They must be starting chemotherapy soon, speak English/Spanish, do less than 90 minutes of exercise per week, and can visit Dana-Farber Cancer Institute for data collection.

What is being tested?

The THRIVE Study tests if a 16-week home-based exercise program (either supervised via Zoom or unsupervised) improves physical activity in minority cancer patients compared to a control group doing stretching exercises.

What are the potential side effects?

Potential side effects from the exercise programs may include typical risks associated with physical activity such as muscle strains or sprains. However, these activities are designed considering participants' health status.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been recently diagnosed with early to mid-stage breast, colorectal, or prostate cancer.

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I am over 18 years old.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I do not have any uncontrolled illnesses like infections or diabetes.

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My cancer has spread to other parts of my body.

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I have another active cancer besides the one being treated.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ evaluated at months 2 and 4

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~evaluated at months 2 and 4

This trial's timeline: 3 weeks for screening, Varies for treatment, and evaluated at months 2 and 4 for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in Physical Activity Participation

Secondary study objectives

Acceptability of Intervention Questionnaire Ratings

Augmentation Index

Biomarkers for Cardiovascular and Metabolic Health - HbA1c

+16 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Unsupervised aerobic and resistance exercise (UNSUP)Experimental Treatment1 Intervention

Participants will be randomly assigned to receive 3x weekly at home, unsupervised aerobic and resistance exercise sessions with a 1x weekly telehealth call with a certified exercise trainer for 16 weeks. Participants will also have a baseline test, mid intervention cardiovascular and strength tests and one postintervention and one follow up visit.

Group II: Supervised aerobic and resistance exercise (SUP)Experimental Treatment1 Intervention

Participants will be randomly assigned to receive 3x weekly at home, virtually supervised aerobic and resistance exercise sessions with a certified exercise trainer for 16 weeks. Participants will also have a baseline test, mid intervention cardiovascular and strength tests and one postintervention and one follow up visit.

Group III: Attention Control (AC)Active Control1 Intervention

Participants will be randomly assigned to receive 3x weekly at home stretching exercise for 16 weeks. Participants will also have a baseline test, mid intervention cardiovascular and strength tests and one postintervention and one follow up visit.

0 / 5Eligibility criteria met