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Incremental vs Conventional Hemodialysis for Kidney Failure

N/A

Recruiting

Led By Andrea Viecelli, Dr

Research Sponsored by The University of Queensland

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Commencing HD as their initial dialysis therapy

Adults (≥ 18 years of age)

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 3, 6, 9, 12, 15 and 18 months

Awards & highlights

No Placebo-Only Group

Summary

This trial will test if dialysis is a safe, practical, and cost-effective way to improve quality of life for dialysis patients and families.

Who is the study for?

The INCH-HD trial is for adults over 18 who are starting hemodialysis (HD) as their first treatment for kidney failure. They must be able to consent to the study and likely stay on HD for at least a year. People with urine output less than half a liter per day can't join.

What is being tested?

This trial compares incremental HD, which gradually increases dialysis frequency, with conventional HD that uses a regular schedule from the start. It aims to see if incremental HD better maintains quality of life and is safe and cost-effective.

What are the potential side effects?

While specific side effects aren't listed here, typical risks associated with hemodialysis may include low blood pressure, muscle cramps, itching, sleep problems, anemia, bone diseases, high blood potassium levels or infection.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am starting hemodialysis as my first dialysis treatment.

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 3, 6, 9, 12, 15 and 18 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 3, 6, 9, 12, 15 and 18 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 3, 6, 9, 12, 15 and 18 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Heath related quality of life

Secondary study objectives

Adverse events and side-effects

Fatigue

Healthcare costs

+13 more

Other study objectives

Patient lifestyle and wellbeing

Time to event

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Group I: Incremental HDExperimental Treatment1 Intervention

Participants randomised to incremental HD will commence HD twice weekly and continue until an indication for an increase to three sessions/week (trigger point) is reached.

Group II: Conventional HDExperimental Treatment1 Intervention

Participants randomised to conventional HD will commence HD thrice weekly from the first HD session.

0 / 2Eligibility criteria met