Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study
(Oxygap 2 Trial)
Trial Summary
What is the purpose of this trial?
The oximeter is used to monitor intensive care patients undergoing oxygen therapy. It indicates pulsed oxygen saturation (SpO2), a reflection of arterial oxygen saturation (SaO2) which enables detection of hypoxemia and hyperoxia, both deleterious state. Current SpO2 recommendations aim to reduce both risk of hypoxemia and hyperoxia. SpO2 is considered the 5th vital sign. Current recommendations for SpO2 targets do not consider the variability of oximeters used in clinical practice. This variability and lack of specification represent an obstacle to an optimal practice of oxygen therapy. Thus, this study aims to compare the SpO2 values of different oximeters (General Electric-GE, Medtronic, Masimo and Nonin) used in clinical practice with the SaO2 reference value obtained by an arterial gas in order to specify the precision and the systematic biases of the oximeters studied. This data will also make it possible to refine the recommendations concerning optimal oxygenation
Research Team
Eligibility Criteria
Inclusion Criteria
Treatment Details
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Who Is Running the Clinical Trial?
Laval University
Lead Sponsor
Dr. Pedro O de Campos-Lima
Laval University
Chief Medical Officer since 1998
MD from Federal University of Juiz de Fora, PhD in Tumor Biology from Karolinska Institute
Dr. Manuel Caruso
Laval University
Chief Executive Officer since 1998
PhD in Virology from Pierre and Marie Curie University