Spinal Cord Stimulation for Spinal Cord Injury

N/A

Waitlist Available

Research Sponsored by Columbia University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Clinical indication for cervical spine surgery

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 0-100 milliseconds after each stimulation event during the experiment

Awards & highlights

No Placebo-Only Group

Summary

"This trial aims to figure out the best way to stimulate the cervical spinal cord after an injury to help with arm and hand muscle movement in spinal cord injury patients."

Who is the study for?

This trial is for individuals who need cervical spine surgery due to conditions like a broken neck, spinal cord injury, or quadriplegia. It's not open to those with stimulation devices in the neck or chest, such as vagal nerve stimulators or pacemakers.

What is being tested?

The study is testing how stimulating the cervical spinal cord during surgery can help arm and hand muscle function after a spinal injury. Researchers want to find out which parts of the cervical spine should be targeted for optimal recovery.

What are the potential side effects?

While specific side effects are not detailed here, epidural electrical stimulation may include risks such as discomfort at the stimulation site, infection risk from surgical procedures, and potential changes in blood pressure.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I need surgery for my neck spine.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 0-100 milliseconds after each stimulation event during the experiment

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~0-100 milliseconds after each stimulation event during the experiment

This trial's timeline: 3 weeks for screening, Varies for treatment, and 0-100 milliseconds after each stimulation event during the experiment for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Efficacy of epidural SCS

Selectivity of epidural SCS

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Arm 1 - Intraoperative ParticipantsExperimental Treatment1 Intervention

Motor evoked responses responses (MEPs) to epidural electrical stimulation (EES) will be tested at cervical segments with and without myelopathy in participants with cervical myelopathy.

0 / 1Eligibility criteria met