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Probiotic

Probiotic for Staph Infection

N/A
Waitlist Available
Research Sponsored by Rothman Institute Orthopaedics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up post-intervention: following 5 days of dietary supplementation
Awards & highlights

Summary

This pilot study is designed to determine if ingestion of Bacillus probiotics can cause alteration in levels of S. aureus colonization in the nose and intestine in preoperative orthopedic patients undergoing elective primary TJA.

Eligible Conditions
  • Staph Infection

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~post-intervention: following 5 days of dietary supplementation
This trial's timeline: 3 weeks for screening, Varies for treatment, and post-intervention: following 5 days of dietary supplementation for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Persistent Staphylococcus aureus colonization
Secondary outcome measures
Changes in microbiome composition

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: ProbioticActive Control1 Intervention
Group II: No interventionPlacebo Group1 Intervention

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Who is running the clinical trial?

Rothman Institute OrthopaedicsLead Sponsor
125 Previous Clinical Trials
22,438 Total Patients Enrolled
~4 spots leftby Sep 2025