Early Feeding for Diabetic Ketoacidosis

Recruiting in Palo Alto (17 mi)

Overseen byKenneth Kenneth, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Texas Tech University Health Sciences Center

No Placebo Group

Trial Summary

What is the purpose of this trial?

Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are common, but serious metabolic disorders are often encountered in intensive care. In the intensive care setting, it is common to withhold food from patients during treatment of DKA. However, there is no evidence or current literature supporting this practice. The following proposed research investigates the initiation of an early diet versus withholding food during the treatment of diabetic ketoacidosis.

Eligibility Criteria

This trial is for men and women aged 18-89 who are in the Medical Intensive Care Unit, can give informed consent, and have diabetic ketoacidosis (high blood sugar over 250 mg/dL, low arterial pH below 7.3, low serum bicarbonate under 15 mEq/L, with ketones in blood or urine).

Inclusion Criteria

You are able to understand and agree to take part in the study.

I am admitted to the ICU for serious medical issues.

I have been diagnosed with diabetic ketoacidosis.

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Treatment Details

Interventions

Early feeding with an oral diet (Other)

Trial OverviewThe study is looking at whether eating early on during treatment for diabetic ketoacidosis helps patients recover better compared to not eating at all. It's testing if starting an oral diet sooner has any benefits.

Participant Groups

2Treatment groups

Experimental Treatment

Active Control

Group I: Early feedingExperimental Treatment1 Intervention

If randomized to the experimental group, patient's diet will be advanced to clear liquid for the first day. On the second day, diet will be advanced to full liquid and advanced up to oral (carb controlled 1600 calories) diet as tolerated.

Group II: Nothing per mouthActive Control1 Intervention

Patient will be kept without PO intake until they are bridged from the insulin drip