Trial Summary
What is the purpose of this trial?
This trial studies the accuracy of a magnetic resonance imaging (MRI) scan in imaging the inside of the chest in patients with thymoma that is newly diagnosed or has come back. An MRI scan may be able to detect if and how far the tumor has spread more accurately than a standard computed tomography (CT) scan.
Eligibility Criteria
This trial is for adults with newly diagnosed or recurrent thymoma who are scheduled for surgery at MD Anderson Cancer Center. It's not open to those under 18, pregnant women, patients with metal in their chest or pacemakers, known allergies to MRI contrast agents (gadolinium), or severe kidney issues.Inclusion Criteria
I am scheduled for surgery at MD Anderson for a new or recurring thymoma.
Exclusion Criteria
Pregnant patients
Patients with a known allergic reaction to gadolinium, who will have their MRI performed without contrast
Patients with an allergy to iodinated contrast material will follow departmental routine policy, that is those with anaphylaxis will have their CT performed without intravenous contrast and others will be prepped as for departmental guidelines for routine chest CT
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Treatment Details
Interventions
- Magnetic Resonance Imaging (Procedure)
Trial OverviewThe study is testing the effectiveness of an MRI scan versus a standard CT scan in accurately imaging and assessing the spread of thymoma within the chest before surgical removal.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Diagnostic (MRI, diaphragm fluoroscopy)Experimental Treatment2 Interventions
Patients undergo an MRI scan over 45-60 minutes and a diaphragm fluoroscopy 30 days before surgery.
Magnetic Resonance Imaging is already approved in United States, United States for the following indications:
🇺🇸 Approved in United States as Lumakras (sotorasib) for:
- Non-small cell lung cancer with KRAS G12C mutation
🇺🇸 Approved in United States as Vectibix (panitumumab) for:
- Advanced colorectal cancer that is wild-type RAS
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
M D Anderson Cancer CenterHouston, TX
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Who Is Running the Clinical Trial?
M.D. Anderson Cancer CenterLead Sponsor
National Cancer Institute (NCI)Collaborator