← Back to Search

Tamsulosin for Postoperative Urinary Retention

Phase < 1

Recruiting

Led By Thomas Bauer, MD

Research Sponsored by Hackensack Meridian Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Planned thoracic oncological surgical procedure of a video assisted oncological surgical procedure for suspected or confirmed cancer.

Males ≥55 years old

Must not have

Current use of Boceprevir

Known diagnosis of congestive heart failure (CHF) and valvular heart disease

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6-8 hours post operative

Awards & highlights

No Placebo-Only Group

Summary

This trial will test if Tamsulosin can reduce the risk of post-surgery urinary retention in older men with cancer surgery. It will also look at how quickly normal urinary function returns.

Who is the study for?

This trial is for men aged 55 or older who are scheduled to have thoracic cancer surgery and haven't used Tamsulosin before. They shouldn't have low blood pressure, a history of heart failure, valvular heart disease, or previous prostate surgery.

What is being tested?

The study tests if Tamsulosin can reduce the high rates of urinary retention after thoracic cancer surgery in older men and how quickly it helps resume normal urinary function post-surgery.

What are the potential side effects?

Tamsulosin may cause dizziness, especially when standing up from sitting or lying down (orthostatic hypotension), allergies in those sensitive to sulfa drugs, and could interact with certain medications like Boceprevir.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am scheduled for a minimally invasive chest cancer surgery.

Select...

I am a man aged 55 or older.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I am currently taking Boceprevir.

Select...

I have been diagnosed with congestive heart failure and heart valve disease.

Select...

I have a history of low blood pressure.

Select...

I have had surgery on my prostate before.

Select...

I am currently taking Tamsulosin.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6-8 hours post operative

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6-8 hours post operative

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6-8 hours post operative for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Amount of residual urine

Number of participants that needed an intervention due to failure to spontaneously urinate

Number of participants that were able to spontaneously void after surgery completion

+2 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Pre-operative Tamsulosin administrationExperimental Treatment1 Intervention

Subjects will be provided with a prescription for Tamsulosin (generic) to be taken 7 days prior to scheduled surgery for thoracic cancer. Tamsulosin dose is set at 0.4mg/day and should be taken daily for seven days prior to their planned surgery date. Study subjects will also be given a diary to record their daily usage. Study subjects should take Tamsulosin on the day of the surgery with a sip of water.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Tamsulosin

2002

Completed Phase 4

~16790

0 / 7Eligibility criteria met