RV Management After LVAD Implantation for Heart Failure

Recruiting in Palo Alto (17 mi)

Overseen byJonathan Grinstein, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University of Chicago

No Placebo Group

Trial Summary

What is the purpose of this trial?

This project evaluates right ventricle (RV) protective strategies after left ventricular assist device (LVAD) implantation.

Research Team

Jonathan Grinstein, MD

Principal Investigator

University of Chicago

Eligibility Criteria

This trial is for adults over 18 who are getting a durable LVAD implant to help their heart pump blood, without needing extra mechanical support for the right side of their heart. It's not for pregnant individuals or those with certain devices already in their heart that they depend on.

Inclusion Criteria

I am getting a long-term left ventricular assist device without support for the right side of my heart.

I am 18 years old or older.

Exclusion Criteria

Pregnant patients

You have a high chance of needing a special heart pump before surgery.

You have a pacemaker and rely on it to help your heart beat regularly.

Treatment Details

Interventions

Standardized RV Management (Other)
Usual Care RV Management (Other)

Trial OverviewThe study is looking at two ways to manage the health of the right ventricle (RV) after an LVAD device has been implanted. One group will receive usual care, while another will follow a standardized RV management plan.

Participant Groups

2Treatment groups

Active Control

Group I: Usual Care RV ManagementActive Control1 Intervention

Physicians will use their own clinical judgement with no prespecified goals for RV management parameters (consistent with SOC)

Group II: Standardized RV ManagementActive Control1 Intervention

Physicians will follow prespecified parameters for RV management (consistent with SOC)