Popular Trials
Taxane
Docetaxel +1 More for Uterine Cancer
Recruiting3 awardsPhase 3
Pueblo, Colorado
This randomized phase III trial is studying gemcitabine hydrochloride, docetaxel, and bevacizumab to see how well they work compared with gemcitabine hydrochloride, docetaxel, and a placebo in treating patients with advanced or recurrent uterine leiomyosarcoma. Drugs used in chemotherapy, such as gemcitabine hydrochloride and docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. It is not yet known whether gemcitabine hydrochloride and docetaxel are more effective when given with or without bevacizumab in treating uterine leiomyosarcoma.
Orexin Antagonist
Lemborexant for Insomnia
Recruiting2 awardsPhase 3
Albuquerque, New Mexico
The key objectives of this study are to determine, using sleep diaries, whether lemborexant at the doses 5 milligrams (mg) and 10 mg is superior to placebo on subjective sleep onset, subjective sleep efficiency, and subjective sleep maintenance in participants with insomnia disorder.
Checkpoint Inhibitor
Targeted Therapy for Advanced Stage Cancer
Recruiting1 awardPhase 2
Albuquerque, New Mexico
This trial is studying how well different targeted drugs work in treating patients with cancer that has progressed after other treatments and has a genomic variant that makes the tumor respond to the drug.
PD-L1 Inhibitor
MEDI4736 +2 More for Non-Hodgkin's Lymphoma
Recruiting1 awardPhase 1
Albuquerque, New Mexico
The purpose of this study is to evaluate the safety, tolerability, and efficacy of MEDI4736 (durvalumab) alone and in combination with either tremelimumab or AZD9150 in adult subjects with relapsed or refractory dIffuse large B-cell lymphoma.
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Phase 3 Trials
Ramucirumab + Pembrolizumab vs Chemotherapy for Non-Small Cell Lung Cancer
Recruiting2 awardsPhase 3
Las Vegas, Nevada
This trial compares ramucirumab+pembrolizumab vs chemo for non-small cell lung cancer. Ramucirumab+pembrolizumab may stop tumors from growing and spreading, while chemo kills/stops cells from dividing/spreading. Results may help find out if this combo is more effective than chemo.
Sodium-glucose cotransporter 2 (SGLT2) inhibitor
Canagliflozin 300 mg +1 More for Type 2 Diabetes
Recruiting1 awardPhase 3
Albuquerque, New Mexico
This trial is testing canagliflozin, a drug that lowers blood sugar, in people with high blood sugar levels. It aims to see how well it works and if it is safe to use over several months.
Monoclonal Antibodies
Tanezumab +1 More for Osteoarthritis
Recruiting2 awardsPhase 3
Tucson, Arizona
The purpose of this study is to compare the long-term joint safety and efficacy (pain relief) of the investigational study drug, tanezumab compared to non-steroidal anti inflammatory drugs (NSAIDs) in subjects with osteoarthritis of the hips or knees.
Antiretroviral
E/C/F/TAF +1 More for Antiretroviral Therapy
Recruiting3 awardsPhase 3
Santa Fe, New Mexico
The primary objective of this study is to evaluate the efficacy of elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide (E/C/F/TAF) fixed-dose combination (FDC) versus elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate (E/C/F/TDF) FDC in HIV-1 positive, antiretroviral treatment-naive adults.
Trials With No Placebo
Ramucirumab + Pembrolizumab vs Chemotherapy for Non-Small Cell Lung Cancer
Recruiting2 awardsPhase 3
Las Vegas, Nevada
This trial compares ramucirumab+pembrolizumab vs chemo for non-small cell lung cancer. Ramucirumab+pembrolizumab may stop tumors from growing and spreading, while chemo kills/stops cells from dividing/spreading. Results may help find out if this combo is more effective than chemo.
Monoclonal Antibodies
Tanezumab +1 More for Osteoarthritis
Recruiting2 awardsPhase 3
Tucson, Arizona
The purpose of this study is to compare the long-term joint safety and efficacy (pain relief) of the investigational study drug, tanezumab compared to non-steroidal anti inflammatory drugs (NSAIDs) in subjects with osteoarthritis of the hips or knees.
Anticoagulant
Rivaroxaban +1 More for Atrial Fibrillation
Recruiting4 awardsPhase 3
Albuquerque, New Mexico
A study for patients with abnormal heart rhythm (atrial fibrillation) who need to undergo cardioversion (procedure to restore normal heart rhythm). The study will compare patients assigned randomly (like flipping a coin) to either Rivaroxaban or vitamin K antagonist (VKA). The study will measure common medical outcomes for this type of patient such as bleeding and stroke.
Monoclonal Antibodies
Octreotide + Interferon/Bevacizumab for Neuroendocrine Tumors
Recruiting2 awardsPhase 3
Alamosa, Colorado
This trial is comparing two treatments for neuroendocrine tumors - octreotide acetate with either recombinant interferon alfa-2b or bevacizumab. The goal is to see if octreotide acetate with recombinant interferon alfa-2b is more effective than with bevacizumab.
Topoisomerase II inhibitors
Etoposide +8 More for Cancer
Recruiting3 awardsPhase 3
Pueblo, Colorado
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage cancer cells. Combining more than one drug with radiation therapy may kill more cancer cells. It is not yet known which combination chemotherapy regimen is most effective in treating Hodgkin's lymphoma. PURPOSE: This randomized phase III trial is studying two different combination chemotherapy regimens and comparing how well they work, with or without radiation therapy, in treating patients with Hodgkin's lymphoma.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.