Depression Clinical Trials in New York, NY

View the best 10 depression medical studies in New York, New York. Access promising new therapies by applying to a New York-based Depression clinical trial.

Trials in New York, New York

Here are the top 10 medical studies for depression in New York, New York

Escitalopram Oxalate

Selective Serotonin Reuptake Inhibitor

Recruiting2 awardsPhase 4

This trial will test if treating depression with the antidepressant escitalopram can affect biological markers related to Alzheimer's disease. It targets people with major depressive disorder to see if reducing their depression can also lower their risk of developing Alzheimer's. The study compares escitalopram to understand its effects on these markers. Escitalopram is commonly used to treat major depressive disorder.

Aticaprant

Recruiting1 awardPhase 3

This trial aims to see if aticaprant is effective in preventing the return of depression symptoms when added to antidepressant therapy in individuals with major depressive disorder who have already responded well to aticaprant treatment

AXS-05

Behavioural Intervention

Recruiting3 awardsPhase 4

This trial is testing AXS-05, a new medication, to see if it can prevent depression from returning in people who have already improved with it. The study focuses on those with major depressive disorder and aims to maintain their balanced brain chemicals to keep them feeling better. AXS-05 (a combination of dextromethorphan and bupropion) has shown positive results in previous trials for major depressive disorder.

PATH-Pain

Behavioral Intervention

Recruiting1 award

This trial tests PATH-Pain therapy in older adults with cognitive issues, chronic pain, and depression. The therapy aims to help them manage pain, improve mood, and enhance thinking skills through regular sessions.

Optimized WellPATH-PREVENT +1 More

Behavioural Intervention

Recruiting1 award

This trial tests WellPATH-PREVENT, a tablet-based program, to help adults aged 50-90 manage emotions and reduce suicide risk. The program teaches recognizing emotional triggers and changing negative thoughts into positive ones.

Connecting and Reflecting Experience (CARE) Program

Behavioral Intervention

Recruiting1 award4 criteria

This trial is testing a group therapy program called CARE for parents with postpartum depression or anxiety. The program helps parents understand their own and their baby's thoughts and feelings to improve mental health and reduce stress. The study targets parents with infants aged 3 to 12 months who are receiving care at Montefiore Medical Center.

Learning through feedback

Behavioral Intervention

Recruiting1 award4 criteria

This trial will study how different feedback timing affects learning and brain function in people with TBI, with and without depression.

Affective Awareness

Behavioral Intervention

Recruiting1 awardPhase 1

This trial tests a new approach to help veterans with serious mental illness who are at risk of suicide. The treatment combines group education sessions and a smartphone app to improve emotional awareness and social functioning. By helping veterans understand their emotions better, the goal is to reduce their suicide risk.

Valera Smart Phone Application

Recruiting1 award

This trial aims to see if a custom mobile app can help young people with lupus stay engaged in their medical care and manage depression. The study focuses on adolescents and young adults from the Bronx, ages 15-24. The app offers personalized support to help them keep up with health appointments and improve their mood.

Tianeptine Sodium

Antidepressant

Recruiting3 awardsPhase 4

This trial tests tianeptine, an antidepressant that targets specific brain receptors, on adults with major depressive disorder who haven't responded to other treatments. The goal is to see if tianeptine can help these patients by working on the brain's natural painkiller system. Tianeptine is known for its unique way of working and its ability to protect the brain from stress.

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Phase 3 Trials

Aticaprant + Antidepressant for Depression

Recruiting1 awardPhase 3

Mount Kisco, New York

This trial aims to see if aticaprant is effective in preventing the return of depression symptoms when added to antidepressant therapy in individuals with major depressive disorder who have already responded well to aticaprant treatment

Behavioural Intervention

Solriamfetol for Depression

Recruiting1 awardPhase 3

Brooklyn, New York

This trial is testing solriamfetol, a medication that may help improve symptoms of depression. It targets adults with major depressive disorder (MDD) who do not have psychotic features. Solriamfetol works by affecting brain chemicals involved in mood regulation, potentially helping to improve mood and reduce depression symptoms.

NMRA-335140 for Depression

Recruiting2 awardsPhase 3

New York, New York

This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.

NMDA Receptor Antagonist

Esketamine vs. Ketamine for Depression

Recruiting2 awardsPhase 3

Milford, Connecticut

This trial aims to compare the effectiveness, acceptability, and side effects of ketamine delivered through an IV and Esketamine taken as a nasal spray for treating treatment-resistant depression. Researchers will assess how

Psychedelic

Psilocybin for Treatment-Resistant Depression

Recruiting1 awardPhase 3

New York, New York

This trial is testing a new medication called COMP360 to help people with severe depression that hasn't improved with other treatments. The study involves adults aged 18 and older. Researchers want to see if a single dose of COMP360 can reduce depression symptoms when given with psychological support.

Pharmacotherapy

Cariprazine for Bipolar Disorder in Youth

Recruiting1 awardPhase 3

Irvington, New Jersey

This trial is testing the safety and effectiveness of Cariprazine for treating depressive episodes in children and teenagers with bipolar I disorder. The goal is to find out if Cariprazine can help young people with this condition. Cariprazine is an atypical antipsychotic recently approved for the treatment of depressive episodes in adults with bipolar I disorder.

Trials With No Placebo

Behavioral Intervention

Self-help Tools for Depression

Recruiting1 award

Princeton, New Jersey

This trial aims to determine if researchers can predict which individuals with depression will benefit more from self-help tools based on behavioral activation or cognitive restructuring. They will use self-reported information and behavior on learning tasks to

Behavioural Intervention

Morning Exercise for Sleep

Recruiting1 award

Piscataway, New Jersey

"This trial aims to study the effects of morning exercise on sleep quality, mood, stress, and productivity in undergraduate students who exercise in the evening and have poor sleep quality. The researchers want to see if

Behavioural Intervention

AXS-05 for Depression

Recruiting3 awardsPhase 4

Mount Kisco, New York

This trial is testing AXS-05, a new medication, to see if it can prevent depression from returning in people who have already improved with it. The study focuses on those with major depressive disorder and aims to maintain their balanced brain chemicals to keep them feeling better. AXS-05 (a combination of dextromethorphan and bupropion) has shown positive results in previous trials for major depressive disorder.

NMRA-335140 for Depression

Recruiting2 awardsPhase 3

New York, New York

This trial is testing a new medication called NMRA-335140 to see if it helps people with major depressive disorder. It includes participants who have no safety concerns. The medication aims to improve mood by affecting brain chemicals.

Behavioral Intervention

App-Based CBT for Anxiety and Depression

Recruiting1 award

New York, New York

This trial tests SilverCloud, an app-based therapy program guided by a therapist, for adolescents with significant mental health symptoms in school-based health centers. The app helps users change negative thoughts and behaviors with therapist support.

Nonsteroidal Anti-inflammatory Drug

Celecoxib for Major Depressive Disorder

Recruiting3 awardsPhase 4

Stony Brook, New York

This trial will test whether the anti-inflammatory drug celecoxib can help reduce symptoms of major depressive disorder by reducing neuroinflammation.

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Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.