Depression Clinical Trials in Raleigh, NC

View the best 10 depression medical studies in Raleigh, North Carolina. Access promising new therapies by applying to a Raleigh-based Depression clinical trial.

Trials in Raleigh, North Carolina

Here are the top 10 medical studies for depression in Raleigh, North Carolina

Healthy Minds Program

Recruiting1 award3 criteria

This trial will look at why adolescent girls are more likely to have depression and boys ADHD, and what factors may be at play during puberty.

Education program +1 More

Behavioral Intervention

Recruiting1 award4 criteria

This trial aims to address the mental health challenges faced by patients who have been in intensive care units by developing a mobile app called Blueprint. This app helps people manage their symptoms and has been shown to reduce

Personalized Integrated Chronotherapy

Behavioral Intervention

Recruiting1 award

This trial tests if adding light exposure and a set sleep routine to regular care can reduce depression and anxiety in pregnant women. It targets women aged 18-40 in late pregnancy who have depression. The treatment aims to adjust the body's natural rhythms and stabilize sleep patterns to improve mood. Light exposure is a promising treatment for depression during pregnancy, being easily accessible, effective, affordable, and safe for both mother and child.

Progesterone +1 More

Hormone Therapy

Recruiting2 awardsPhase 4

"This trial aims to understand how hormonal changes during the menstrual cycle impact mood symptoms in women with depression that worsens before menstruation. They will investigate how estrogen and progesterone levels affect pleasure and reward

Cognitive-Behavioral Therapy (CBT) +1 More

Behavioural Intervention

Recruiting1 award6 criteria

This trial will compare CBT & MBT, two treatments for depression & anxiety in autistic adults, to see which is more effective.

Psilocybin

Psychedelic Therapy

Recruiting2 awardsPhase 3

"This trial aims to test how effective psilocybin-assisted therapy is in treating depression. Participants will undergo screening, receive psilocybin treatment, and attend follow-up sessions over a year.

Quit on the Go App

Behavioural Intervention

Recruiting1 award

This trial will test a new smartphone app called Quit on the Go, designed to help people with serious mental illness quit smoking. The study will compare this app to traditional methods, with both groups also using nicotine patches and gum. The goal is to see if the app helps more people quit smoking and if it is cost-effective.

Mindfulness-based treatment for insomnia (MBTI) +1 More

Behavioural Intervention

Recruiting1 award4 criteria

"This trial will compare two types of therapy (Cognitive Behavioral Therapy for Insomnia and Mindfulness-Based Treatment for Insomnia) delivered through telemedicine to treat insomnia and depressive symptoms in individuals with mild to

Lumateperone

Behavioural Intervention

Recruiting1 awardPhase 3

"This trial is studying the effectiveness of a new treatment for children with bipolar disorder who are also experiencing major depressive episodes. The study is being conducted at multiple locations and will involve random assignment of participants to receive

One Talk at a Time: Race

Behavioural Intervention

Recruiting1 award

This trial is testing an online video intervention to help parents talk to their kids about race. The goal is to see if it increases motivation and skills in having these conversations, and if it leads to better mental and academic outcomes for kids.

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Trials With No Placebo

Behavioral Intervention

Single Session Psychotherapy for Depression

Recruiting1 award2 criteria

Chapel Hill, North Carolina

This trial aims to see if a single session intervention can help reduce psychological issues in adults with moderate depression. They want to know if this intervention is acceptable to participants, if it can be done in one

Behavioral Intervention

Teacher-Led Mental Health Care for Children

Recruiting1 award

Chapel Hill, North Carolina

This trial aims to test a new system of mental health care for children, delivered by teachers. Around 300 participants are estimated to take part in the study. The study will evaluate the reach, effectiveness

Behavioral Intervention

Coping Skills Training for Anxiety and Stress

Recruiting1 award4 criteria

Durham, North Carolina

This trial aims to address the mental health challenges faced by patients who have been in intensive care units by developing a mobile app called Blueprint. This app helps people manage their symptoms and has been shown to reduce

Procedure

RE104 for Postpartum Depression

Recruiting1 awardPhase 2

Chapel Hill, North Carolina

This trial is testing whether a single injection of RE104 can help reduce depression in women who have moderate-to-severe postpartum depression. The goal is to see if this treatment works effectively. The exact way RE104 works isn't detailed, but it likely helps by affecting brain chemicals related to mood.

Behavioural Intervention

CBT-I vs. MBTI for TBI-Related Insomnia

Recruiting1 award4 criteria

Fort Bragg, North Carolina

"This trial will compare two types of therapy (Cognitive Behavioral Therapy for Insomnia and Mindfulness-Based Treatment for Insomnia) delivered through telemedicine to treat insomnia and depressive symptoms in individuals with mild to

Behavioral Intervention

Mindfulness Therapy for Migraines

Recruiting1 award

Winston-Salem, North Carolina

This trial is testing a type of therapy called Mindfulness-Based Cognitive Therapy, provided over the phone, through video calls, or as part of regular care with added support. It aims to help people with migraines and depressive symptoms by teaching them to focus on the present moment and understand their thought patterns better. Mindfulness-Based Cognitive Therapy (MBCT) was developed to prevent relapse in recurrent depression by combining cognitive behavioral therapy and meditative techniques.

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Frequently Asked Questions

Do I need insurance to participate in a trial?

Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).

Is there any support for travel costs?

Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.

Will I know what medication I am taking?

This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.

How long do clinical trials last?

Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.

Do you verify all the trials on your website?

All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.

How quickly will I hear back from a clinical trial?

Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.