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Trials for Head And Neck Squamous Cell Carcinoma Patients
Behavioral Intervention
Cough and Expiratory Training for Pneumonia Risk after Head and Neck Cancer Treatment
Recruiting1 award
Houston, Texas
This trial will test if exercising the muscles involved in coughing and swallowing can help reduce the risk of pneumonia for patients who have had radiation for head and neck cancer.
Tyrosine Kinase Inhibitor
Entrectinib for Solid Tumors
Recruiting1 awardPhase 2
Phoenix, Arizona
This trial is testing a new drug, entrectinib, for patients with different types of solid tumors that have a gene fusion. Patients will be assigned to different groups depending on their tumor type and gene fusion.
Platinum-based Chemotherapy
CACTUX for Head and Neck Cancer
Recruiting1 awardPhase 2
Little Rock, Arkansas
This trial is testing a new cancer treatment called CACTUX. It's a combination of 3 drugs, and the investigators want to see if it's effective and has fewer side effects than the standard treatment.
Trials for Head And Neck Cancers Patients
Behavioral Intervention
Cough and Expiratory Training for Pneumonia Risk after Head and Neck Cancer Treatment
Recruiting1 award
Houston, Texas
This trial will test if exercising the muscles involved in coughing and swallowing can help reduce the risk of pneumonia for patients who have had radiation for head and neck cancer.
Tyrosine Kinase Inhibitor
Entrectinib for Solid Tumors
Recruiting1 awardPhase 2
Phoenix, Arizona
This trial is testing a new drug, entrectinib, for patients with different types of solid tumors that have a gene fusion. Patients will be assigned to different groups depending on their tumor type and gene fusion.
Platinum-based Chemotherapy
CACTUX for Head and Neck Cancer
Recruiting1 awardPhase 2
Little Rock, Arkansas
This trial is testing a new cancer treatment called CACTUX. It's a combination of 3 drugs, and the investigators want to see if it's effective and has fewer side effects than the standard treatment.
Behavioural Intervention
Smoking Cessation Treatment for Head & Neck Cancer Patients
Recruiting1 awardPhase < 1
Houston, Texas
This trial is designed to study and compare the effectiveness of two types of counseling for cancer patients who want to quit smoking: Acceptance and Commitment Therapy (ACT) and Motivational and Behavioral Counseling (MBC).
Trials for Metastatic Patients
Tyrosine Kinase Inhibitor
Entrectinib for Solid Tumors
Recruiting1 awardPhase 2
Phoenix, Arizona
This trial is testing a new drug, entrectinib, for patients with different types of solid tumors that have a gene fusion. Patients will be assigned to different groups depending on their tumor type and gene fusion.
CAR T-cell Therapy
Adoptive Cell Transfer + Interleukin 2 for Cancer
Recruiting1 awardPhase 1
La Jolla, California
This trial will test whether taking tumor cells and growing them in the lab to create more tumor-fighting cells, which are then put back into the patient, can help fight cancer when the patient's immune system is suppressed.
PD-1 Inhibitor
Pembrolizumab + Radiotherapy for Head and Neck Cancer
Recruiting2 awardsPhase 3
La Jolla, California
This trial is testing whether adding pembrolizumab to radiotherapy (with or without cisplatin) before and after surgery improves outcomes in people with newly diagnosed, resectable head and neck squamous cell carcinoma.
Trials for P16 Positive Patients
PD-1 Inhibitor
Pembrolizumab + Radiotherapy for Head and Neck Cancer
Recruiting2 awardsPhase 3
La Jolla, California
This trial is testing whether adding pembrolizumab to radiotherapy (with or without cisplatin) before and after surgery improves outcomes in people with newly diagnosed, resectable head and neck squamous cell carcinoma.
Alkylating agents
Chemotherapy + Reduced-Dose Radiation for Throat Cancer
Recruiting1 awardPhase 2
Columbia, Missouri
This trial will explore giving standard dose chemotherapy and radiation therapy to sites of disease including all lymph nodes involved with HPV-positive oropharyngeal cancer, but administering lower doses of radiation therapy to the lymph nodes that are not known to be involved with cancer.
Trials for PD-L1 Positive Patients
Monoclonal Antibodies
INBRX-106 + Pembrolizumab for Lung Cancer
Recruiting1 awardPhase 1 & 2
Duarte, California
This trial is studying a new drug to see if it is safe and effective at treating locally advanced or metastatic non small cell lung cancer when given in combination with pembrolizumab (Keytruda).
Checkpoint Inhibitor
Nivolumab + Relatlimab/Ipilimumab for Head and Neck Cancer
Recruiting1 awardPhase 2
Pittsburgh, Pennsylvania
This trial is testing whether adding an anti-PD1 antibody to either an anti-CTLA4 antibody or an anti-LAG3 antibody will help improve the body's response to the tumor in people with resectable locally advanced HNSCC.
Phase 3 Trials
Radiation
Radiation Therapy + Cetuximab for Head and Neck Cancer
Recruiting3 awardsPhase 3
Birmingham, Alabama
This trial is comparing radiation therapy alone to radiation therapy given with the drug cetuximab to see if it is more effective in treating patients who have had surgery for locally advanced head and neck cancer.
PD-1 Inhibitor
Pembrolizumab + Radiotherapy for Head and Neck Cancer
Recruiting2 awardsPhase 3
La Jolla, California
This trial is testing whether adding pembrolizumab to radiotherapy (with or without cisplatin) before and after surgery improves outcomes in people with newly diagnosed, resectable head and neck squamous cell carcinoma.
Mitotic Inhibitor
Buparlisib + Chemotherapy for Head and Neck Cancer
Recruiting2 awardsPhase 3
North Brunswick, New Jersey
This trial is testing a combination of two drugs, buparlisib and paclitaxel, for patients with head and neck cancer that has returned or spread after other treatments. Buparlisib is taken regularly to stop cancer cells from growing, and paclitaxel is given periodically to prevent them from multiplying. The goal is to see if this combination works better than using paclitaxel alone.
Platinum-containing Compound
Chemotherapy + Radiation Therapy for Head and Neck Cancer
Recruiting1 awardPhase 2 & 3
Birmingham, Alabama
This trial is testing how well radiation therapy works in combination with different drugs after surgery to treat patients with high-risk stage III-IV head and neck cancer.
Trials With No Placebo
Behavioral Intervention
Cough and Expiratory Training for Pneumonia Risk after Head and Neck Cancer Treatment
Recruiting1 award
Houston, Texas
This trial will test if exercising the muscles involved in coughing and swallowing can help reduce the risk of pneumonia for patients who have had radiation for head and neck cancer.
Tyrosine Kinase Inhibitor
Entrectinib for Solid Tumors
Recruiting1 awardPhase 2
Phoenix, Arizona
This trial is testing a new drug, entrectinib, for patients with different types of solid tumors that have a gene fusion. Patients will be assigned to different groups depending on their tumor type and gene fusion.
Platinum-based Chemotherapy
CACTUX for Head and Neck Cancer
Recruiting1 awardPhase 2
Little Rock, Arkansas
This trial is testing a new cancer treatment called CACTUX. It's a combination of 3 drugs, and the investigators want to see if it's effective and has fewer side effects than the standard treatment.
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Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.