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What is Centany
MupirocinThe Generic name of this drug
Treatment SummaryMupirocin is a type of antibiotic that works differently than other antibiotics. It is made naturally by the organism Pseudomonas fluorescens and is used to treat impetigo, a bacterial skin infection caused by Staphylococcus aureus and Streptococcus pyogenes, as well as other secondary bacterial skin infections. It is also sometimes used to treat nasal carriage of Staphylococci when administered intranasally. Mupirocin is only available in topical forms and is sold under the brand name Bactroban.
Bactrobanis the brand name
Centany Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Bactroban
Mupirocin
1996
98
Approved as Treatment by the FDA
Mupirocin, also called Bactroban, is approved by the FDA for 4 uses which include staphylococcus aurea colonization of the nasal passage and Bacterial Infections .staphylococcus aurea colonization of the nasal passage
Bacterial Infections
Impetigo
Communicable Diseases
Effectiveness
How Centany Affects PatientsMupirocin can be used to treat many different types of bacterial infections, such as staphylococcus aureus and streptococcus pyogenes. It works by preventing bacteria from making proteins needed for them to survive. Tests have found that it is effective in over 90% of patients with skin infections, but it can develop resistance in some cases. Resistance is more common in staphylococci that are resistant to other antibiotics.
How Centany works in the bodyMupirocin works by interrupting the production of proteins and RNA in bacteria. It binds to a specific enzyme that helps convert isoleucine and tRNA into isoleucyl-tRNA. By blocking this enzyme, mupirocin stops bacteria from producing proteins and RNA. At lower concentrations, mupirocin stops bacteria from growing, while at higher concentrations it can actually kill up to 99% of susceptible bacteria in 24 hours.
When to interrupt dosage
The proposed dose of Centany is contingent upon the diagnosed state, such as Communicable Diseases, Bacterial Infections and staphylococcus aurea colonization of the nasal passage. The measure of dosage is contingent upon the process of delivery (e.g. Ointment or Cream) delineated in the table below.Condition
Dosage
Administration
Impetigo
0.02 mg/mg, , 0.0215 mg/mg, 2.0 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Ointment - Nasal, Nasal, Kit, Kit - Topical
Impetigo
0.02 mg/mg, , 0.0215 mg/mg, 2.0 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Ointment - Nasal, Nasal, Kit, Kit - Topical
Communicable Diseases
0.02 mg/mg, , 0.0215 mg/mg, 2.0 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Ointment - Nasal, Nasal, Kit, Kit - Topical
staphylococcus aurea colonization of the nasal passage
0.02 mg/mg, , 0.0215 mg/mg, 2.0 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Ointment - Nasal, Nasal, Kit, Kit - Topical
Impetigo
0.02 mg/mg, , 0.0215 mg/mg, 2.0 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Ointment - Nasal, Nasal, Kit, Kit - Topical
Bacterial Infections
0.02 mg/mg, , 0.0215 mg/mg, 2.0 %
, Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Ointment - Nasal, Nasal, Kit, Kit - Topical
Warnings
Centany ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Mupirocin may interact with Pulse Frequency
Common Centany Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Mupirocin.
(R)-warfarin
Moderate
The risk or severity of bleeding can be increased when Mupirocin is combined with (R)-warfarin.
(S)-Warfarin
Moderate
The risk or severity of bleeding can be increased when Mupirocin is combined with (S)-Warfarin.
4-hydroxycoumarin
Moderate
The risk or severity of bleeding can be increased when Mupirocin is combined with 4-hydroxycoumarin.
Acenocoumarol
Moderate
The risk or severity of bleeding can be increased when Mupirocin is combined with Acenocoumarol.
Centany Toxicity & Overdose RiskThe maximum toxic dose of mupirocin in rats is 5000mg/kg. No studies have been done to evaluate if mupirocin can cause cancer. Tests in animals and bacteria did not show any signs of it damaging genes. In tests involving male and female rats, there were no signs that mupirocin affected their fertility. Mupirocin has been found in human milk, so it should be used cautiously in pregnant women. Clinical trials showed that mupirocin is safe and effective for children aged 2 months to 16 years old.
Centany Novel Uses: Which Conditions Have a Clinical Trial Featuring Centany?
An active clinical trial is currently underway to investigate the potential of Centany to address Bacterial Infections, Impetigo and Communicable Diseases.Condition
Clinical Trials
Trial Phases
Bacterial Infections
0 Actively Recruiting
staphylococcus aurea colonization of the nasal passage
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Impetigo
0 Actively Recruiting
Impetigo
1 Actively Recruiting
Not Applicable
Impetigo
0 Actively Recruiting
Centany Reviews: What are patients saying about Centany?
5Patient Review
11/27/2010 My dermatologist prescribed me this medication to help with a boil I had. After just one week of use, the infection was gone and there was barely any swelling or redness. I later learned from the doctor that the medication is great at killing bacteria.
5Patient Review
9/5/2015 I've found this to be an effective medication, especially when applied several times throughout the day with a light bandage.
5Patient Review
9/23/20075Patient Review
9/28/2010Patient Q&A Section about centany
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does mupirocin do to bacteria?
"Mupirocin is unique among antibiotics in that it inhibits the activity of isoleucyl-tRNA synthetase, an enzyme required for bacterial protein synthesis. Without this enzyme, bacteria are unable to produce proteins and ultimately die."
Answered by AI
What is Centany used for?
"Mupirocin is a cream or ointment that is applied to the skin and is used to treat moderate to severe small skin infections. It has very few side effects."
Answered by AI
What is mupirocin used to treat?
"Mupirocin topical cream is used to treat skin lesions that have become infected with specific bacteria. Mupirocin topical ointment is used to treat impetigo. This medicine kills bacteria or prevents their growth. This medicine is only available with a doctor's prescription."
Answered by AI
Is Centany an OTC?
"Centany is a prescription medicine used to treat the symptoms of Impetigo, Secondary Skin Infection and Elimination of MRSA Colonization. Centany may be used alone or with other medications. Centany belongs to a class of drugs called Antibacterials, Topical."
Answered by AI