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What is Lovaza
Omega-3-acid ethyl estersThe Generic name of this drug
Treatment SummaryOmega-3-acid ethyl esters are prescription drugs that contain fatty acids EPA and DHA, which are used alongside dietary changes to reduce triglyceride levels in adults with very high triglycerides (over 500mg/dL). Omega-3-acid ethyl esters are sold worldwide under the brand name Lovaza.
Tandem DHAis the brand name
Lovaza Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Tandem DHA
Omega-3-acid ethyl esters
2007
57
Approved as Treatment by the FDA
Omega-3-acid ethyl esters, also called Tandem DHA, is approved by the FDA for 2 uses which include Severe Hypertriglyceridemia (sHTG) and Hypertriglyceridemia .Severe Hypertriglyceridemia (sHTG)
Helps manage Severe Hypertriglyceridemia (sHTG)
Hypertriglyceridemia
Helps manage Severe Hypertriglyceridemia (sHTG)
Effectiveness
How Lovaza Affects PatientsOmega-3-acid ethyl esters can help lower triglyceride levels, increase the breakdown of fat, prevent fat from being released into the bloodstream, clear out triglycerides faster, and decrease the amount of VLDL-C (very low density lipoprotein cholesterol) in the body.
How Lovaza works in the bodyOmega-3-acid ethyl esters help reduce triglyceride levels in the body. The exact mechanism is unknown, but it is thought that the drug blocks enzymes involved in the production of triglycerides, increases fat metabolism, and increases the breakdown of triglycerides. It also competes with other enzymes to decrease the production of VLDL-C.
When to interrupt dosage
The recommended dosage of Lovaza is contingent upon the identified condition. The measure of dosage differs in accordance with the procedure of delivery noted in the table below.Condition
Dosage
Administration
Hypertriglyceridemia
, 1000.0 mg, 300.0 mg, 900.0 mg, 1.0 mg/mg, 500.0 mg, 250.0 mg, 667.0 mg, 1050.0 mg, 430.0 mg, 400.0 mg, 200.0 mg, 310.1 mg, 1220.0 mg
Capsule, liquid filled, Oral, Capsule, liquid filled - Oral, , Capsule, Capsule - Oral, Capsule, Delayed Release, Capsule, Delayed Release - Oral, Kit, Kit - Oral, Tablet - Oral, Tablet
Warnings
Lovaza ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Omega-3-acid Ethyl Esters may interact with Pulse Frequency
Common Lovaza Drug Interactions
Drug Name
Risk Level
Description
(R)-warfarin
Minor
The risk or severity of bleeding can be increased when Omega-3-acid ethyl esters is combined with (R)-warfarin.
(S)-Warfarin
Minor
The risk or severity of bleeding can be increased when Omega-3-acid ethyl esters is combined with (S)-Warfarin.
4-hydroxycoumarin
Minor
The risk or severity of bleeding can be increased when Omega-3-acid ethyl esters is combined with 4-hydroxycoumarin.
Abciximab
Minor
The risk or severity of bleeding can be increased when Omega-3-acid ethyl esters is combined with Abciximab.
Acenocoumarol
Minor
The risk or severity of bleeding can be increased when Omega-3-acid ethyl esters is combined with Acenocoumarol.
Lovaza Toxicity & Overdose RiskOmega-3-acid ethyl esters have not been found to be mutagenic or cause chromosomal damage in rats, nor have they been found to affect fertility. There is no evidence from human studies on the safety of this drug during pregnancy, but studies in rats have indicated that high doses may harm an unborn baby. In lactating rats, this drug has been found to be excreted in breastmilk at levels 6 to 14 times higher than in the mother's bloodstream, but it is not known if this could harm a nursing infant. Omega-3-acid ethyl esters have not been tested in children or
Lovaza Novel Uses: Which Conditions Have a Clinical Trial Featuring Lovaza?
Presently, 4 clinical trials are assessing the potential of Lovaza to ameliorate Hypertriglyceridemia.Condition
Clinical Trials
Trial Phases
Hypertriglyceridemia
9 Actively Recruiting
Phase 3, Phase 2
Lovaza Reviews: What are patients saying about Lovaza?
5Patient Review
7/9/2017 I never have an after taste with this product, and I've found it to be really effective in lowering my triglyceride levels. It's also reasonably priced, especially for a generic.
5Patient Review
4/26/2019 I highly recommend looking into ways to get this drug at a discount; it really helped me lower my triglyceride levels. I didn't experience any negative side effects, and it's been over a year since I started taking it.
5Patient Review
7/14/2015 I started taking Lovaza a month ago in order to get my triglycerides under control. However, after taking it for a month and getting my labs retaken, I've seen that all of the numbers on my lipid panel have gone up by 75 points or more. Everything is now in the high range. I will be stopping this medication today and never taking it again!
5Patient Review
5/4/2016 I found that this treatment made me fart a lot. They were rank and nasty, but I enjoyed it. My turds stank too.
5Patient Review
5/20/2014Patient Q&A Section about lovaza
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is a common side effect of Lovaza?
"The possible side effects of LOVAZA are as follows: burping, infection, flu symptoms, upset stomach, a change in your sense of taste, back pain and skin rash. If you experience any of these side effects, consult your doctor. These are not the only possible side effects of LOVAZA."
Answered by AI
What is the drug Lovaza used for?
"Omega-3 acid is used to lower the triglyceride levels in adults. It is typically used with a low-fat and low-cholesterol diet. Jan 9, 2022"
Answered by AI
What is the generic name for Lovaza?
"Omega-3-acid ethyl esters (Lovaza) and icosapent ethyl (Vascepa) are both oral capsules that are swallowed. Lovaza can be taken once or twice a day, and Vascepa is taken twice a day. Both products are formulations of omega-3 fatty acids (from fish oil)."
Answered by AI
Is Lovaza same as fish oil?
"The biggest difference between OTC fish oil supplements and prescription Lovaza is that Lovaza has more EPA and DHA in each capsule."
Answered by AI