Metipranolol

Open Angle Glaucoma, Ocular Hypertension
Treatment
4 FDA approvals
17 Active Studies for Metipranolol

What is Metipranolol

MetipranololThe Generic name of this drug
Treatment SummaryPropranolol is a drug used to treat irregular heartbeats, high blood pressure, and glaucoma. It works by blocking the action of beta-1 and beta-2 receptors in the body.
OptiPranololis the brand name
Metipranolol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
OptiPranolol
Metipranolol
1989
4

Approved as Treatment by the FDA

Metipranolol, otherwise known as OptiPranolol, is approved by the FDA for 4 uses like Ocular Hypertension and Open Angle Glaucoma (OAG) .
Ocular Hypertension
Helps manage Ocular Hypertension
Open Angle Glaucoma (OAG)
Helps manage Open Angle Glaucoma (OAG)
Open Angle Glaucoma
Helps manage Open Angle Glaucoma (OAG)
Ocular Hypertension
Helps manage Ocular Hypertension

Effectiveness

How Metipranolol Affects PatientsMetipranolol is a drug used to treat high pressure in the eye (ocular hypertension or open-angle glaucoma). It does not have any impact on the heart, nerves or muscle tissue, and instead works to reduce pressure in the eye. This drug does not lead to a narrowing of the pupil or any issues with vision, unlike some other drugs used for treating glaucoma.
How Metipranolol works in the bodyMetipranolol works by attaching to the beta1 and beta2 adrenergic receptors. It has no effect on stimulating the body, but does have a slight effect on stabilizing the cell membrane and decreasing activity in the heart. Its primary effect is to reduce the amount of fluid in the eye, and there is some evidence that it also helps it flow out.

When to interrupt dosage

The suggested dosage of Metipranolol is contingent upon the diagnosed condition. The sum of dosage is contingent upon the mode of administration outlined in the table beneath.
Condition
Dosage
Administration
Ocular Hypertension
3.0 mg/mL,
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic
Open Angle Glaucoma
3.0 mg/mL,
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic

Warnings

Metipranolol has six contraindications; thus, it should not be mixed with any of the circumstances specified in the following table.Metipranolol Contraindications
Condition
Risk Level
Notes
Heart Failure
Do Not Combine
Atrioventricular Block
Do Not Combine
Asthma
Do Not Combine
symptomatic sinus bradycardia
Do Not Combine
Shock, Cardiogenic
Do Not Combine
Asthma
Do Not Combine
There are 20 known major drug interactions with Metipranolol.
Common Metipranolol Drug Interactions
Drug Name
Risk Level
Description
Aliskiren
Minor
Metipranolol may increase the hypotensive activities of Aliskiren.
Ambrisentan
Minor
Metipranolol may increase the hypotensive activities of Ambrisentan.
Angiotensin 1-7
Minor
Metipranolol may increase the hypotensive activities of Angiotensin 1-7.
Azilsartan medoxomil
Minor
Metipranolol may increase the hypotensive activities of Azilsartan medoxomil.
BQ-123
Minor
Metipranolol may increase the hypotensive activities of BQ-123.

Metipranolol Novel Uses: Which Conditions Have a Clinical Trial Featuring Metipranolol?

34 clinical trials are presently underway to assess the utility of Metipranolol for therapeutic management of Open Angle Glaucoma.
Condition
Clinical Trials
Trial Phases
Ocular Hypertension
12 Actively Recruiting
Phase 3, Phase 4, Phase 1, Phase 2, Not Applicable
Open Angle Glaucoma
10 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1

Patient Q&A Section about metipranolol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is metipranolol a beta blocker?

"These drugs therefore can produce a wide range of potential adverse effects, as well as being ineffective in some patients.

Glaucoma is a condition that can be treated with a variety of different pharmacological options. However, some drugs, like the beta blockers Timolol, Carteolol, Metipranolol, and Levobunolol, work by blocking both beta 1 and beta 2 receptors, and thus can produce a range of potential adverse effects. Additionally, these drugs may not be effective in all patients."

Answered by AI

What is metipranolol used for?

"Metipranolol is a beta blocker that is used to treat increased pressure in the eye that is caused by open-angle glaucoma or ocular hypertension. It can be used alone or with other medicines."

Answered by AI

How does metipranolol help glaucoma?

"Ophthalmic metipranolol is used to treat glaucoma, a condition in which increased pressure in the eye can lead to gradual loss of vision. Metipranolol belongs to a group of medications called beta-blockers. These drugs work by reducing pressure in the eye."

Answered by AI

How to use eye drops?

"To use eye drops correctly, tilt your head back and look up. With one hand, pull your lower eyelid down and away from your eyeball — this makes a “pocket” for the drops. With the other hand, hold the eye drop bottle upside down with the tip just above the pocket. Squeeze the prescribed number of eye drops into the pocket."

Answered by AI

Clinical Trials for Metipranolol

Have you considered Metipranolol clinical trials? We made a collection of clinical trials featuring Metipranolol, we think they might fit your search criteria.
Have you considered Metipranolol clinical trials? We made a collection of clinical trials featuring Metipranolol, we think they might fit your search criteria.
Have you considered Metipranolol clinical trials? We made a collection of clinical trials featuring Metipranolol, we think they might fit your search criteria.
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