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What is Seroquel
QuetiapineThe Generic name of this drug
Treatment SummaryQuetiapine is a type of antipsychotic medication approved by the FDA in 1997. It is used to treat schizophrenia, major depression, and bipolar disorder. Quetiapine has been found to be effective and have fewer side effects compared to other drugs like clozapine and olanzapine and is suitable for some patients who are sensitive to other medications.
Seroquelis the brand name
Seroquel Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Seroquel
Quetiapine
1997
700
Approved as Treatment by the FDA
Quetiapine, also known as Seroquel, is approved by the FDA for 2 uses which include Bipolar Disorder and Depression .Bipolar Disorder
Used in combination with other therapies
Depression
Effectiveness
How Seroquel Affects PatientsQuetiapine can help to treat symptoms of schizophrenia and major depression by targeting certain brain chemicals. It can also help with both depression and mania in bipolar disorder. However, this drug should not be given to children under 10 years of age as it can lead to suicidal thoughts or behavior. Elderly patients should not take this drug either, as it has been linked to an increased risk of death.
How Seroquel works in the bodyQuetiapine works in the body to treat symptoms of schizophrenia, depression, and bipolar disorder. It does this by blocking certain receptors in the brain, such as serotonin and dopamine. Quetiapine also works on other receptors that can cause drowsiness, low blood pressure, and dry mouth.
When to interrupt dosage
The advised dose of Seroquel is reliant upon the diagnosed affliction, including Mental Depression, Bipolar Disorder and Acute Coryza. The amount of dosage is contingent upon the technique of administration as evidenced in the following table.Condition
Dosage
Administration
Generalized Anxiety Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Parkinson's Disease
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Schizophrenia
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Schizophrenia
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Acute Coryza
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Bipolar Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Bipolar Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Behcet Syndrome
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Depression
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Post Traumatic Stress Disorder
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Mental Depression
, 50.0 mg, 150.0 mg, 200.0 mg, 300.0 mg, 400.0 mg, 100.0 mg, 25.0 mg, 550.0 mg
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, film coated, Tablet, film coated - Oral, Tablet, Tablet - Oral, Tablet, multilayer, extended release, Tablet, multilayer, extended release - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral
Warnings
There are 20 known major drug interactions with Seroquel.Common Seroquel Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Quetiapine may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Quetiapine is combined with Aclidinium.
Alfuzosin
Major
Quetiapine may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Quetiapine may increase the antipsychotic activities of Amisulpride.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Quetiapine is combined with Anagrelide.
Seroquel Toxicity & Overdose RiskThe safest amount of quetiapine for rats to take is 2000mg/kg. Signs of an overdose include feeling very sleepy, a fast heart rate, and low blood pressure. In clinical trials, taking up to 30 grams of quetiapine did not cause death, but one person died after taking 13.6 grams. If someone has overdosed on quetiapine, they may need help with their breathing, have their stomach emptied, and be given activated charcoal and a laxative. It is also important to monitor their heart and avoid drugs that can affect the QT interval.
Seroquel Novel Uses: Which Conditions Have a Clinical Trial Featuring Seroquel?
705 active trials are being conducted to assess the potential of Seroquel in providing relief for Depression, Schizophrenia and Bipolar Disorder.Condition
Clinical Trials
Trial Phases
Parkinson's Disease
41 Actively Recruiting
Not Applicable, Phase 1, Phase 4, Phase 2, Phase 3, Early Phase 1
Generalized Anxiety Disorder
201 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 1, Phase 3, Early Phase 1
Post Traumatic Stress Disorder
239 Actively Recruiting
Not Applicable, Early Phase 1, Phase 2, Phase 3, Phase 4, Phase 1
Acute Coryza
1 Actively Recruiting
Not Applicable
Depression
190 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 1, Early Phase 1, Phase 3
Bipolar Disorder
0 Actively Recruiting
Schizophrenia
118 Actively Recruiting
Not Applicable, Early Phase 1, Phase 4, Phase 3, Phase 2, Phase 1
Mental Depression
2 Actively Recruiting
Not Applicable
Behcet Syndrome
1 Actively Recruiting
Not Applicable
Bipolar Disorder
0 Actively Recruiting
Schizophrenia
37 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Seroquel Reviews: What are patients saying about Seroquel?
5Patient Review
7/25/2022 After two weeks of taking this medication, I noticed a significant decrease in anxiety levels. Additionally, my mood became more stable and I was less irritable. I would recommend this to anyone struggling with bipolar disorder or severe anxiety.
5Patient Review
10/5/2022 This medication has definitely helped me sleep better at night. The only downside is that I have occasional nightmares. Other than that, my mood is much improved and hallucinations are no longer an issue.
5Patient Review
9/6/2022 Seroquel has been hugely effective in curbing my mania, and as a result, the crashes that come after. I also find that my mind is more clear and less agitated overall.
4Patient Review
2/5/2022 I've struggled with debilitating panic attacks for years, but this treatment has really helped. I take 100mg daily and it's made a world of difference. The only downside is that it gives me the munchies!
3.3Patient Review
12/1/2021 I was diagnosed with depression and this medication really helps me sleep at night. The only downside is that I need to take Adderall in the morning or else I can't get out of bed until noon.
3Patient Review
10/3/2022 I didn't like this pill. I took it for two months and then had to stop because my body got used to it and I couldn't sleep at night. My moods were all over the place and I was wide awake all the time with racing thoughts that I couldn't control. It made me feel numb to the world and I didn't want to be around anyone.
2.7Patient Review
3/16/2022 Seroquel was successful in treating my depression and anxiety-related mood swings; however, I experienced debilitating drowsiness as a side effect. This made it difficult for me to get through the day without needing a nap.
1.7Patient Review
6/12/2022 I gain a lot of weight very quickly since I started taking this medication, which has been incredibly frustrating. Additionally, it's made me feel tired and groggy all the time. Overall, not recommended.
1.7Patient Review
9/28/2022 Seroquel did very little to help with my bipolar II diagnosis. I felt groggy, dull, and gained weight while taking it. Nightmares also. Very unpleasant and frustrating. Switched to Lamotragine and felt much better.
1Patient Review
8/18/2022 This drug is pure poison. Seroquel gives you diabetes, high triglycerides and puts stress on your liver. When I started taking it, my doctor put me on 1000mg to start. I slept for a week straight. I'm down to 200mg now, and I take a week off of this drug every so often to cleanse my body from the poison.
Patient Q&A Section about seroquel
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What does Seroquel make you feel like?
"Confusion, headache, drowsiness, agitation, constipation, weight gain, dry mouth, and blurred vision are all possible side effects of the medication. Feb 11, 2022"
Answered by AI
What kind of narcotic is Seroquel?
"Seroquel is an atypical antipsychotic drug approved by the U.S. Food and Drug Administration (FDA) to treat schizophrenia and bipolar disorder."
Answered by AI
Is Seroquel a sleeping pill?
"The primary use of Ambien is to treat insomnia while Seroquel is used off-label, or for a different purpose, to also treat insomnia. Seroquel is primarily intended to treat schizophrenia in adults and children aged thirteen years or older."
Answered by AI
Is Seroquel the same as Xanax?
"Seroquel is used to treat schizophrenia, major depression, and bipolar disorder while Xanax is used to treat panic attacks and anxiety disorders. These two drugs come from different drug classes with Seroquel being an antipsychotic medication and Xanax being a benzodiazepine."
Answered by AI
What does Seroquel do to you?
"Quetiapine is a medication that affects the brain in order to treat those with schizophrenia. It is classified as a second generation antipsychotic (SGA) or atypical antipsychotic. By affecting the levels of dopamine and serotonin, quetiapine is able to improve thinking, mood, and behavior."
Answered by AI