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What is Travoprost
TravoprostThe Generic name of this drug
Treatment SummaryTravoprost ophthalmic solution is a medication used to treat open-angle glaucoma and ocular hypertension. It works by lowering the pressure inside the eye and is a synthetic form of prostaglandin F2alpha. It is the only prostaglandin analog approved by the FDA for first-line treatment of glaucoma that does not contain the preservative benzalkonium chloride. Travoprost is also approved in the EU for use in children as young as 2 months who have ocular hypertension or glaucoma.
Travatanis the brand name
Travoprost Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Travatan
Travoprost
2001
15
Approved as Treatment by the FDA
Travoprost, also known as Travatan, is approved by the FDA for 3 uses such as Ocular Hypertension and Open Angle Glaucoma .Ocular Hypertension
Helps manage Ocular Hypertension
Open Angle Glaucoma
Helps manage Open Angle Glaucoma (OAG)
Glaucoma
Helps manage Increased Intra Ocular Pressure (IOP)
Effectiveness
How Travoprost Affects PatientsTravoprost is a medication that is made from a synthetic form of a hormone that helps regulate blood pressure. It is quickly broken down into an active form in the cornea, and binds to a receptor in the body that helps regulate blood pressure.
How Travoprost works in the bodyTravoprost is a medication that helps reduce the pressure inside the eye. It's a full agonist, meaning it binds to the prostaglandin FP receptor and stimulates it. This increases the flow of fluid out of the eye, lowering the pressure. The effects of Travoprost can be seen in a couple of hours, and the effects last for over 24 hours with just a single dose.
When to interrupt dosage
The advised measure of Travoprost is contingent upon the diagnosed condition, for example, Open Angle Glaucoma, Ocular Hypertension and Enhanced Intra Ocular Pressure (IOP). The dose is contingent upon the technique of delivery (e.g. Solution or Ophthalmic) expressed in the accompanying table.Condition
Dosage
Administration
Glaucoma
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Open Angle Glaucoma
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Ocular Hypertension
, 0.04 mg/mL, 0.004 %, 0.03 mg/mL, 0.003 %
, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic
Warnings
Travoprost ContraindicationsCondition
Risk Level
Notes
Attemping to get pregnant
Do Not Combine
Common Travoprost Drug Interactions
Drug Name
Risk Level
Description
Acebutolol
Minor
Travoprost may increase the hypotensive activities of Acebutolol.
Aliskiren
Minor
Travoprost may increase the hypotensive activities of Aliskiren.
Alprenolol
Minor
Travoprost may increase the hypotensive activities of Alprenolol.
Ambrisentan
Minor
Travoprost may increase the hypotensive activities of Ambrisentan.
Amlodipine
Minor
Travoprost may increase the hypotensive activities of Amlodipine.
Travoprost Toxicity & Overdose RiskNo cases of overdose have been reported for travoprost. If a topical overdose does occur, it should be flushed out with lukewarm water. Treatment for an oral overdose should be symptomatic and supportive. Travoprost is not recommended for pregnant women or those who are breastfeeding, as the medication could be passed to the fetus or baby. Animal studies have found excretion of travoprost and its metabolites in breast milk. There is no data on the effects of travoprost on human fertility, but animal studies did not find any negative effects on fertility at doses 250 times higher than the recommended human
Travoprost Novel Uses: Which Conditions Have a Clinical Trial Featuring Travoprost?
34 active clinical trials are currently evaluating the potential of Travoprost in attenuating Ocular Hypertension, Increased Intra Ocular Pressure (IOP) and Open Angle Glaucoma.Condition
Clinical Trials
Trial Phases
Open Angle Glaucoma
11 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1
Glaucoma
0 Actively Recruiting
Ocular Hypertension
14 Actively Recruiting
Phase 3, Phase 4, Phase 1, Phase 2, Not Applicable
Travoprost Reviews: What are patients saying about Travoprost?
5Patient Review
11/9/2021 I've had great results with this medication, but the new packaging is harder to use. I have arthritis in my hands, so it's difficult for me to hold the bottle and keep my eye open at the same time. As a result, I end up wasting a drop or two every night.
4.7Patient Review
3/30/2012 TravatanZ was much gentler on my eyes than the previous prescription I had been using.
Patient Q&A Section about travoprost
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is travoprost discontinued?
"The company that makes IZBA has notified the FDA that the drug will no longer be produced."
Answered by AI
What are the side effects of travoprost eye drops?
"The following side effects may occur: blurred vision, eye redness/discomfort/itching, feeling as if something is in your eye, dry eyes, tearing, eyelid crusting, increase in eyelash number/length/thickness, darkening of the eyelashes and eyelids, eyelid changes, or increased sensitivity to light."
Answered by AI
What is travoprost eye drops for?
"Travoprost is a medication used to manage ocular hypertension and open-angle glaucoma, by regulating the pressure in the eye. Excessive pressure in the eye can cause pain or vision changes. Travoprost is a prostaglandin, a type of medication that works by decreasing fluid production in the eye."
Answered by AI
Is travoprost and latanoprost the same?
"The study's concluded that travoprost is a more effective treatment than latanoprost and timolol for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension."
Answered by AI