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Intervention for Wound Bleeding

Phase < 1
Waitlist Available
Led By Nicholas Golda, MD
Research Sponsored by University of Missouri-Columbia
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
All adult (18 years or older) patients presenting for Mohs micrographic surgery (MMS) for the treatment of melanoma or nonmelanoma skin cancer (NMSC) with a wound that will be healing by granulation
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up three days
Awards & highlights

Summary

This study is evaluating whether a drug may help reduce bleeding after surgery for skin cancer.

Eligible Conditions
  • Wound Bleeding

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~three days
This trial's timeline: 3 weeks for screening, Varies for treatment, and three days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Rate of clinic evaluations of postoperative hemorrhagic complications
Rate of postoperative hemorrhagic complications
Rate of treatment interventions for postoperative hemorrhagic complications
Secondary outcome measures
Types of postoperative hemorrhagic complications

Side effects data

From 2012 Phase 4 trial • 100 Patients • NCT00740116
22%
Readmissions
14%
Postoperative infections
10%
Re-operations
4%
Thromboembolic events
100%
80%
60%
40%
20%
0%
Study treatment Arm
Placebo Group
Tranexamic Group

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: InterventionExperimental Treatment1 Intervention
Topical application of tranexamic acid to granulating wound defect status post Mohs micrographic surgery.
Group II: PlaceboPlacebo Group1 Intervention
Topical application of normal saline to granulating wound defect status post Mohs micrographic surgery.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tranexamic acid
FDA approved

Find a Location

Who is running the clinical trial?

University of Missouri-ColumbiaLead Sponsor
367 Previous Clinical Trials
628,355 Total Patients Enrolled
Nicholas Golda, MDPrincipal InvestigatorUniversity of Missouri-Columbia
1 Previous Clinical Trials
160 Total Patients Enrolled
~13 spots leftby Aug 2025
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