Device
Electrophysiology-Guided Care for Left Bundle Branch Block After TAVI
Recruiting1 award3 criteria
Montreal, Quebec
This trial will compare an electrophysiology-based algorithm to standard clinical follow-up in patients who have had TAVI and new left bundle branch block. The goal is to see if the electrophysiology-based algorithm can reduce syncope, hospitalization, and death.
Transcatheter Valve Replacement
TAVR vs SAVR for Aortic Valve Stenosis
Recruiting1 award3 criteria
Phoenix, Arizona
This trial is comparing the safety and effectiveness of the Medtronic TAVR system to SAVR in the treatment of severe aortic stenosis in low risk patients. The continued access phase will be single-arm and non-randomized.
Transcatheter Aortic Valve
Portico Valve for Aortic Stenosis
Recruiting1 award9 criteria
Birmingham, Alabama
This trial is testing a new heart valve replacement device for patients with severe heart valve issues who are too high-risk for traditional surgery. The device is inserted through a blood vessel, making the procedure less invasive.
Surgery
Transcatheter vs Surgical Valve Replacement for Bicuspid Aortic Valve
Recruiting1 award3 criteria
Los Angeles, California
This trial is comparing two treatments, transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR), for patients with severe aortic stenosis and a
Procedure
SESAME Procedure for Hypertrophic Cardiomyopathy
Recruiting1 award
Atlanta, Georgia
"This trial is testing a new procedure called SESAME in adults with a condition where the heart's pumping chambers are separated by a thick wall. This thick wall can cause reduced blood flow and serious heart disease
Behavioral Intervention
Automated Alerts for Heart Valve Issues
Recruiting1 award1 criteria
Kansas City, Missouri
This trial will test if using automated notifications from Tempus Next can help doctors identify and evaluate patients who may need Valve Intervention (VI). They will look at how these notifications affect whether patients undergo procedures for
Popular Filters
Trials for AS Patients
Angiotensin Receptor Blockers for Aortic Stenosis
Recruiting2 awardsPhase 4
Québec, Quebec
This trial is testing whether medications that help relax blood vessels can slow down the worsening of aortic stenosis and heart muscle problems. The study focuses on patients with mild-to-moderate aortic stenosis. These medications work by blocking chemicals that can make these heart conditions worse. They are a new class of drugs with broad therapeutic potential in cardiovascular disease.
Transcatheter Aortic Valve Replacement
Aortic Valve Replacement for Aortic Stenosis
Recruiting1 award7 criteria
New Haven, Connecticut
This trial compares two methods of heart valve replacement in patients with severe narrowing of the heart valve. It aims to see if one method is better at improving blood flow and reducing symptoms without needing major surgery.
Artificial Intelligence
AI-Enhanced Detection for Aortic Stenosis
Recruiting0 awards1 criteria
Santa Clara, California
This trial will test how well artificial intelligence can predict the risk of aortic stenosis using data from portable ECG and cardiac ultrasound devices. """ This trial will assess how accurate AI
Trials for Aortic Valve Stenosis Patients
Angiotensin Receptor Blockers for Aortic Stenosis
Recruiting2 awardsPhase 4
Québec, Quebec
This trial is testing whether medications that help relax blood vessels can slow down the worsening of aortic stenosis and heart muscle problems. The study focuses on patients with mild-to-moderate aortic stenosis. These medications work by blocking chemicals that can make these heart conditions worse. They are a new class of drugs with broad therapeutic potential in cardiovascular disease.
Transcatheter Heart Valve
TAVR for Aortic Stenosis
Recruiting1 award4 criteria
Morristown, New Jersey
This trial tests advanced heart valves that can be inserted without open-heart surgery in patients with a narrowed and stiff aortic valve due to calcium buildup. The new valve is placed through a small cut and guided to the heart, where it replaces the damaged valve. This minimally invasive procedure has recently become the only lifesaving solution for patients who cannot tolerate standard surgical valve replacement.
Transcatheter Aortic Valve Replacement
Aortic Valve Replacement for Aortic Stenosis
Recruiting1 award7 criteria
New Haven, Connecticut
This trial compares two methods of heart valve replacement in patients with severe narrowing of the heart valve. It aims to see if one method is better at improving blood flow and reducing symptoms without needing major surgery.
Transcatheter Aortic Valve Replacement
TAVR Valves for Aortic Valve Stenosis
Recruiting1 award5 criteria
Detroit, Michigan
This trial looks at two types of valves used to treat heart conditions. The first type is called a supra-annular valve, and the second type is called an annular valve. The trial will compare how well each type of valve works in patients with small annuli (a heart condition that affects the size of the heart).
Polymer Aortic Valve
Foldax Tria Aortic Valve Replacement for Aortic Valve Disease
Recruiting1 award4 criteria
Indianapolis, Indiana
This trial is testing a new artificial heart valve made from polymer material in patients who need a replacement for their damaged or malfunctioning aortic valve. The new valve helps regulate blood flow from the heart, aiming to improve heart function and patient safety. The polymeric valve has been developed to last longer and work better than current options.
ECG Monitoring Device
ECG Monitoring for Aortic Stenosis
Recruiting1 award1 criteria
Québec, Quebec
This trial is looking at whether arrhythmias are more common in people with aortic stenosis who are candidates for TAVI. If so, then detecting and treating these arrhythmias before the TAVI procedure may improve patient outcomes.
Trials With No Placebo
Transcatheter Heart Valve
TAVR for Aortic Stenosis
Recruiting1 award4 criteria
Morristown, New Jersey
This trial tests advanced heart valves that can be inserted without open-heart surgery in patients with a narrowed and stiff aortic valve due to calcium buildup. The new valve is placed through a small cut and guided to the heart, where it replaces the damaged valve. This minimally invasive procedure has recently become the only lifesaving solution for patients who cannot tolerate standard surgical valve replacement.
Transcatheter Aortic Valve Replacement
Aortic Valve Replacement for Aortic Stenosis
Recruiting1 award7 criteria
New Haven, Connecticut
This trial compares two methods of heart valve replacement in patients with severe narrowing of the heart valve. It aims to see if one method is better at improving blood flow and reducing symptoms without needing major surgery.
Transcatheter Aortic Valve Replacement
TAVR Valves for Aortic Valve Stenosis
Recruiting1 award5 criteria
Detroit, Michigan
This trial looks at two types of valves used to treat heart conditions. The first type is called a supra-annular valve, and the second type is called an annular valve. The trial will compare how well each type of valve works in patients with small annuli (a heart condition that affects the size of the heart).
Polymer Aortic Valve
Foldax Tria Aortic Valve Replacement for Aortic Valve Disease
Recruiting1 award4 criteria
Indianapolis, Indiana
This trial is testing a new artificial heart valve made from polymer material in patients who need a replacement for their damaged or malfunctioning aortic valve. The new valve helps regulate blood flow from the heart, aiming to improve heart function and patient safety. The polymeric valve has been developed to last longer and work better than current options.
ECG Monitoring Device
ECG Monitoring for Aortic Stenosis
Recruiting1 award1 criteria
Québec, Quebec
This trial is looking at whether arrhythmias are more common in people with aortic stenosis who are candidates for TAVI. If so, then detecting and treating these arrhythmias before the TAVI procedure may improve patient outcomes.
Transcatheter Aortic Valve Replacement (TAVR)
TAVR with CENTERA THV for Aortic Stenosis
Recruiting1 award4 criteria
Los Angeles, California
This trial will test the Edwards CENTERA Transcatheter Heart Valve (THV) System in patients with severe aortic valve stenosis who are at intermediate risk for surgical aortic valve replacement (SAVR).
View More Related Trials
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.