Pre-Operative Radiation Therapy for Breast Cancer
(SPORT-DS Trial)

Recruiting in Palo Alto (17 mi)

Age: 65+

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Michael Yassa

No Placebo Group

Trial Summary

What is the purpose of this trial?

To study a single dose of preoperative partial radiotherapy to a low-risk breast tumour. The radiotherapy will be goven 3 months before surgery.

Research Team

Eligibility Criteria

This trial is for women aged 65 or older with low-risk breast cancer. Eligible participants have a small tumor (less than 2cm), no nodal disease, positive estrogen receptor status, negative Her2, and are planning partial mastectomy. Exclusions include prior cancers (except certain skin cancers), large tumors, lobular carcinoma only, positive lymph nodes, and serious non-cancer illnesses.

Inclusion Criteria

You have had markers placed at the treatment site before starting the trial.

My breast cancer was confirmed by a biopsy within the last 3 months.

My tumor is smaller than 2cm according to a physical exam and ultrasound.

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Exclusion Criteria

Psychiatric or addictive disorders which would preclude obtaining informed consent or adherence to protocol

I have had cancer before, but if it was skin cancer, it's okay.

I am under 65 years old.

See 19 more

Treatment Details

Interventions

Single Pre-Operative Radiation Therapy - with Delayed Surgery (Radiation Therapy)

Trial OverviewThe study tests a single dose of preoperative partial radiotherapy given three months before surgery on patients with low-risk breast tumors. It aims to assess the effectiveness and safety of this approach compared to traditional treatment timelines.

Participant Groups

1Treatment groups

Experimental Treatment

Group I: Single Pre-Operative Radiation Therapy with Delayed SurgeryExperimental Treatment1 Intervention

Single Pre-Operative Radiation Therapy with Delayed Surgery