Nutritional Supplement for Type 2 Diabetes

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 1

Waitlist Available

Sponsor: Nimble Science Ltd.

No Placebo Group

Trial Summary

What is the purpose of this trial?This study aims to study the effect of an oral nutrition supplement to help manage type-2 diabetes by capturing the metagenomic fingerprint of the small-intestine.

Eligibility Criteria

Adults aged 40-65 with type 2 diabetes, HbA1c levels between 6.5% and 9.5%, BMI of 20-29.9, stable weight, and taking up to three oral diabetic medications including Metformin can join this trial. They must not be pregnant or breastfeeding, have used certain supplements or antibiotics recently, have clotting disorders or active cancer, engage in strenuous exercise, or plan to become pregnant.

Inclusion Criteria

Has type 2 diabetes as evidenced by their medical history charts and is able to maintain number of medications, type and dose throughout the duration of the study

My HbA1c level is between 6.5% and 9.5%.

My BMI is between 20 and 29.9.

+9 more

Exclusion Criteria

I haven't taken any antibiotics (except skin ones) in the last 12 weeks.

I don't have clotting or bleeding issues, or I'm safely on Plavix or similar.

I have not had a blood transfusion in the last 3 weeks.

+26 more

Participant Groups

The trial is testing an oral nutritional supplement's impact on the gut microbiome of diabetic patients. Participants will consume the supplement and undergo assessments to see if it helps manage their diabetes by altering the microorganisms in their small intestine.

1Treatment groups

Experimental Treatment

Group I: Interventional ArmExperimental Treatment1 Intervention

Ingestion of the ONS