Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Presbyopia

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 1

Waitlist Available

Sponsor: LENZ Therapeutics, Inc

No Placebo Group

Trial Summary

What is the purpose of this trial?

This is a single-center, open-label, randomized study to assess the plasma pharmacokinetic profile of LNZ101 and LNZ100.

Eligibility Criteria

Inclusion Criteria

Be able and willing to follow all instructions and attend all study visits

Be able and willing to provide written informed consent and sign a Health Information Portability and Accountability Act (HIPAA) form prior to any study procedure being performed

Be 45-75 years of age of either sex and any race or ethnicity

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Exclusion Criteria

You have any ongoing health condition, either in your whole body or in your eyes, except for vision problems that can be fixed with glasses or contact lenses.

You have any eye problems that could affect how well eye drops are absorbed.

Have known contraindications or sensitivity to the use of the investigational drug or its components, or any other medications required by the protocol

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