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Cancer Vaccine

modRNA Vaccine for Flu

Phase 1
Waitlist Available
Research Sponsored by Pfizer
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years

Summary

This trial is testing a new vaccine called Pandemic Influenza modRNA (pdmFlu) Vaccine to see if it can prevent the flu. They are looking for participants between the ages

Who is the study for?
This trial is for healthy adults aged 18 to 49 who can commit to the study's schedule and procedures. They must not have received any flu vaccine in the past 6 months and should be able to give informed consent.
What is being tested?
The trial is testing a new mRNA vaccine for pandemic influenza, comparing it with a licensed quadrivalent influenza vaccine (QIV) and a placebo. Participants will get shots on day 1 and day 21 without knowing which one they receive.
What are the potential side effects?
Potential side effects may include pain at the injection site, fever, fatigue, headache, muscle pains similar to those experienced with other vaccines but specific risks of pdmFlu Vaccine will be studied.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

5Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: pdmFlu vaccine dose CExperimental Treatment1 Intervention
Group II: pdmFlu vaccine dose BExperimental Treatment1 Intervention
Group III: pdmFlu vaccine dose AExperimental Treatment1 Intervention
Group IV: Licensed influenza vaccineActive Control1 Intervention
Group V: PlaceboPlacebo Group1 Intervention

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

PfizerLead Sponsor
4,669 Previous Clinical Trials
17,861,827 Total Patients Enrolled
6 Trials studying Vaccines
23,825 Patients Enrolled for Vaccines
Pfizer CT.gov Call CenterStudy DirectorPfizer
3,553 Previous Clinical Trials
14,902,829 Total Patients Enrolled
7 Trials studying Vaccines
23,993 Patients Enrolled for Vaccines
~18 spots leftby Apr 2025
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