Mango Consumption for Satiety
Recruiting in Palo Alto (17 mi)
Age: 18 - 65
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Recruiting
Sponsor: San Diego State University
Disqualifiers: Smoker, Pregnant, Dietary supplements, others
No Placebo Group
Trial Summary
What is the purpose of this trial?
The objective of the study is to determine the effects of fresh mango pulp consumption on satiety and metabolic parameters in overweight/obese adults.
Do I need to stop taking my current medications for the trial?
The trial requires that you do not need any medication for metabolic disorders, so if you are taking such medications, you may not be eligible to participate.
What data supports the effectiveness of fresh mango pulp consumption for satiety?
Is mango consumption generally safe for humans?
How does fresh mango pulp consumption as a treatment for satiety differ from other treatments?
Fresh mango pulp consumption is unique because it not only promotes greater feelings of fullness compared to refined snacks like low-fat cookies, but it also helps stabilize blood sugar levels more effectively than dried mango or white bread. This makes it a natural and nutritious option for improving satiety and managing post-meal blood sugar levels.123411
Research Team
Eligibility Criteria
This trial is for adults aged 18-55 with a BMI between 27 and 40, who are not pregnant, do not smoke, don't need dietary supplements or medications for metabolic disorders, and have no allergies to mango or gluten.Inclusion Criteria
Your body mass index (BMI) is between 27 and 40.
I am between 18 and 55 years old.
Exclusion Criteria
Pregnant woman
I am on medication for a metabolic disorder.
Required dietary supplement use
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Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
2-4 weeks
Treatment
Participants consume 100 kcal of either mango fruit or low fat cookies daily
12 weeks
Regular visits for outcome measures at baseline, week 4, and week 12
Follow-up
Participants are monitored for safety and effectiveness after treatment
4 weeks
Treatment Details
Interventions
- Fresh Mango Pulp Consumption (Behavioural Intervention)
Trial OverviewThe study aims to see if eating fresh mango pulp affects how full people feel and their heart health-related numbers compared to having a low-fat cookie. Participants will be given either the fruit or the cookie in this research.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: Mango fruitExperimental Treatment1 Intervention
Subjects consume 100 kcal of mango fruit daily for 12 weeks.
Group II: Low fat cookiesActive Control1 Intervention
Subjects consume 100 kcal of low fat cookies daily for 12 weeks.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
School of Exercise and Nutritional Sciences, SDSUSan Diego, CA
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Who Is Running the Clinical Trial?
San Diego State University
Lead Sponsor
Trials
182
Patients Recruited
119,000+
Findings from Research
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Fresh Mango Consumption Promotes Greater Satiety and Improves Postprandial Glucose and Insulin Responses in Healthy Overweight and Obese Adults.Pinneo, S., O'Mealy, C., Rosas, M., et al.[2022]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Effects of fresh vs dried mango consumption on satiety and postprandial glucose in healthy adults.Stamper, C., Safadi, S., Gehr, A., et al.[2023]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
The effect of fruit in different forms on energy intake and satiety at a meal.Flood-Obbagy, JE., Rolls, BJ.[2021]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Mango Consumption Is Associated with Improved Nutrient Intakes, Diet Quality, and Weight-Related Health Outcomes.Papanikolaou, Y., Fulgoni, VL.[2022]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Influences of harvest date and location on the levels of beta-carotene, ascorbic acid, total phenols, the in vitro antioxidant capacity, and phenolic profiles of five commercial varieties of mango (Mangifera indica L.).Manthey, JA., Perkins-Veazie, P.[2013]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Estimated daily intake and safety of FD&C food-colour additives in the US population.Bastaki, M., Farrell, T., Bhusari, S., et al.[2018]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Safety impact--the risk/benefits of functional foods.Pascal, G.[2021]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements.Schilter, B., Andersson, C., Anton, R., et al.[2019]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Safety of dried aerial parts of Hoodia parviflora as a novel food pursuant to Regulation (EC) No 258/97.Turck, D., Bresson, JL., Burlingame, B., et al.[2023]
The study estimated the theoretical maximum daily intake of Sunset Yellow (SY) food dye in the Brazilian population, finding that average consumption did not exceed the acceptable daily intake (ADI) of 4.0 mg/kg body weight for most groups.
However, certain demographics, particularly adolescents and individuals in specific urban and rural areas, may consume levels of SY that approach or exceed the ADI, potentially posing health risks.
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
Estimate of the theoretical maximum daily intake of Sunset Yellow FCF by the Brazilian population.Feitosa, LCA., Rodrigues, PDS., Da Silva, AS., et al.[2019]
NCBI (Pubmed)
pubmed.ncbi.nlm.nih.gov
[In vitro and in vivo effects of mango pulp (Mangifera indica cv. Azucar) in colon carcinogenesis].Corrales-Bernal, A., Amparo Urango, L., Rojano, B., et al.[2016]
References
Fresh Mango Consumption Promotes Greater Satiety and Improves Postprandial Glucose and Insulin Responses in Healthy Overweight and Obese Adults. [2022]
Effects of fresh vs dried mango consumption on satiety and postprandial glucose in healthy adults. [2023]
The effect of fruit in different forms on energy intake and satiety at a meal. [2021]
Mango Consumption Is Associated with Improved Nutrient Intakes, Diet Quality, and Weight-Related Health Outcomes. [2022]
Influences of harvest date and location on the levels of beta-carotene, ascorbic acid, total phenols, the in vitro antioxidant capacity, and phenolic profiles of five commercial varieties of mango (Mangifera indica L.). [2013]
Estimated daily intake and safety of FD&C food-colour additives in the US population. [2018]
Safety impact--the risk/benefits of functional foods. [2021]
Guidance for the safety assessment of botanicals and botanical preparations for use in food and food supplements. [2019]
Safety of dried aerial parts of Hoodia parviflora as a novel food pursuant to Regulation (EC) No 258/97. [2023]
Estimate of the theoretical maximum daily intake of Sunset Yellow FCF by the Brazilian population. [2019]
[In vitro and in vivo effects of mango pulp (Mangifera indica cv. Azucar) in colon carcinogenesis]. [2016]