Flu and COVID-19 Vaccines for Coronavirus and Influenza
Recruiting in Palo Alto (17 mi)
+25 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 1 & 2
Recruiting
Sponsor: BioNTech SE
No Placebo Group
Trial Summary
What is the purpose of this trial?
The purpose of this study is to learn about how the flu and COVID vaccines act when given alone or when mixed together. This study is seeking healthy participants aged 18 or older. All participants in this study will receive only 1 shot to their arm, either a flu or COVID vaccine, alone or mixed. Participants will take part in this study for about 6 months, and participants will need to visit the clinical study site at least 4 times.
Research Team
PC
Pfizer CT.gov Call Center
Principal Investigator
Pfizer
Eligibility Criteria
Healthy individuals aged 18 or older are eligible for this study, which involves receiving a single shot of either a flu or COVID vaccine, alone or in combination. Participants will be involved for approximately 6 months and must visit the study site at least four times.Inclusion Criteria
I am 18 years old or older.
Healthy participants who are determined by medical history, physical examination (if clinically required), and clinical judgement of the investigator to be eligible for inclusion in the study
Exclusion Criteria
I have been vaccinated against COVID-19 within the last 150 days.
I have not had a flu vaccine in the last 150 days.
I haven't taken flu antivirals like Tamiflu in the last 6 months.
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
2-4 weeks
Treatment
Participants receive one shot of either a flu or COVID vaccine, alone or mixed
1 day
1 visit (in-person)
Follow-up
Participants are monitored for safety and effectiveness after receiving the vaccine
6 months
At least 4 visits (in-person)
Treatment Details
Interventions
- Investigational Influenza and COVID-19 Combination Vaccine (Virus Therapy)
Trial OverviewThe trial is testing how different vaccines (flu and COVID-19) work when given separately or together. This includes licensed influenza vaccines, an approved COVID-19 vaccine, as well as investigational flu and COVID-19 vaccines.
Participant Groups
30Treatment groups
Experimental Treatment
Active Control
Group I: Arm RRExperimental Treatment1 Intervention
Medium Dose Investigational Influenza Vaccine (2b)
Group II: Arm QQExperimental Treatment1 Intervention
Low Dose Investigational Influenza Vaccine (2a)
Group III: Arm PPExperimental Treatment1 Intervention
Medium Dose Investigational Influenza Vaccine (1b)
Group IV: Arm OOExperimental Treatment1 Intervention
Medium Dose Investigational Influenza Vaccine (1a)
Group V: Arm NNExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 9)
Group VI: Arm MMExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (Medium Dose Combination 8)
Group VII: Arm LLExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 7)
Group VIII: Arm KKExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 6)
Group IX: Arm JJExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (Medium Dose Combination 5)
Group X: Arm IIExperimental Treatment1 Intervention
Low Dose COVID-19 Vaccine (1c)
Group XI: Arm HHExperimental Treatment1 Intervention
Low Dose COVID-19 Vaccine (1b)
Group XII: Arm GGExperimental Treatment1 Intervention
Low Dose COVID-19 Vaccine (1a)
Group XIII: Arm GExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 4)
Group XIV: Arm FExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 3)
Group XV: Arm EExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (Medium Dose Combination 2)
Group XVI: Arm DDExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 4)
Group XVII: Arm DExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 1)
Group XVIII: Arm CCExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 3)
Group XIX: Arm CExperimental Treatment1 Intervention
Low Dose COVID-19 Vaccine ( 1c)
Group XX: Arm BBExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (Medium Dose Combination 2)
Group XXI: Arm BExperimental Treatment1 Intervention
Low Dose COVID-19 Vaccine ( 1b)
Group XXII: Arm AAExperimental Treatment1 Intervention
Investigational Influenza and COVID-19 Combination Vaccine (High Dose Combination 1)
Group XXIII: Arm AExperimental Treatment1 Intervention
Low Dose COVID-19 Vaccine (1a)
Group XXIV: Arm TTActive Control1 Intervention
Licensed Influenza Vaccine (2)
Group XXV: Arm HActive Control1 Intervention
Low Dose Licensed COVID-19 Vaccine
Group XXVI: Arm IActive Control1 Intervention
Licensed Influenza Vaccine (1)
Group XXVII: Arm UUActive Control1 Intervention
Licensed Influenza Vaccine (3)
Group XXVIII: Arm SSActive Control1 Intervention
Low Dose Licensed COVID-19 Vaccine
Group XXIX: Arm EEActive Control1 Intervention
Low Dose Licensed COVID-19 Vaccine
Group XXX: Arm FFActive Control1 Intervention
Licensed Influenza Vaccine (2)
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Clinical Research ConsultingMilford, CT
East-West Medical Research InstituteHonolulu, HI
Diablo Clinical Research, Inc.Walnut Creek, CA
Las Vegas Clinical TrialsNorth Las Vegas, NV
More Trial Locations
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Who Is Running the Clinical Trial?
BioNTech SE
Lead Sponsor
Trials
84
Recruited
120,000+
Prof. Dr. Ugur Sahin
BioNTech SE
Chief Executive Officer since 2008
MD from University of Cologne
Prof. Özlem Türeci
BioNTech SE
Chief Medical Officer since 2018
MD from Saarland University
Pfizer
Industry Sponsor
Trials
4712
Recruited
50,980,000+
Known For
Vaccine Innovations
Top Products
Viagra, Zoloft, Lipitor, Prevnar 13
Albert Bourla
Pfizer
Chief Executive Officer since 2019
PhD in Biotechnology of Reproduction, Aristotle University of Thessaloniki
Patrizia Cavazzoni
Pfizer
Chief Medical Officer
MD from McGill University