REM-001 Photodynamic Therapy for Breast Cancer

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byAlina Markova, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 2

Recruiting

Sponsor: Kintara Therapeutics, Inc.

No Placebo Group

Prior Safety Data

Trial Summary

What is the purpose of this trial?This trial tests REM-001 Therapy, which includes a drug and a light treatment, on patients whose disease is stable or improving. The drug makes cancer cells sensitive to light, helping to destroy them when light is applied.

Eligibility Criteria

This trial is for adults with breast cancer that has spread to the skin, causing symptoms like pain or ulceration. Participants must have tried at least two systemic therapies and be on certain treatments for 3 months. They should not be suitable for surgery or radiation therapy, have stable brain metastases if present, no major recent surgeries or other serious medical conditions, and agree to use contraception.

Inclusion Criteria

The investigator has determined that you are suitable for photodynamic therapy (PDT).

I am a male willing to use contraception during and up to 90 days after treatment.

I can take care of myself and am up and about more than half of my waking hours.

+18 more

Exclusion Criteria

I stopped using corticosteroids for my condition 4 weeks before starting the study treatment.

I have an ongoing hepatitis B or C infection.

I have not had certain local treatments on my cancer in the last 12 weeks.

+16 more

Participant Groups

The study tests REM-001 photodynamic therapy in patients with cutaneous metastatic breast cancer. It's an open-label trial aiming to confirm dosing and timing of response using digital photography to evaluate how well skin tumors respond to this treatment.

1Treatment groups

Experimental Treatment

Group I: REM-001 photodynamic therapy (PDT)Experimental Treatment1 Intervention

Single arm study. All enrolled patients receive REM-001 therapy