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Radiation
Radiation Therapy for Follicular Lymphoma
N/A
Recruiting
Led By May Tsao, MD
Research Sponsored by Sunnybrook Health Sciences Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 month and 3 month
Awards & highlights
No Placebo-Only Group
Summary
This trial is looking at what the best dose of radiation is to treat low grade follicular lymphoma while minimizing side effects.
Who is the study for?
This trial is for adults over 18 with low-grade (grade 1-2) follicular lymphoma that hasn't been treated with radiation before. It's for those who need radiation for local disease control, have non-bulky targets under 7cm, and can consent to treatment. Pregnant individuals or those on systemic therapy for lymphoma within the last 3 months are excluded.
What is being tested?
The study is testing a specific intermediate dose of radiation (12 Gy in 6 daily fractions) to see if it effectively treats follicular lymphoma while reducing both immediate and long-term side effects. The goal is an excellent response rate with minimal toxicity.
What are the potential side effects?
Potential side effects may include skin reactions at the treatment site, fatigue, mild discomfort or pain, and possible late-onset effects related to irradiated tissues which will be closely monitored.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1 month and 3 month
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 month and 3 month
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Complete response within the radiated volume at 1month post radiation
Secondary study objectives
Overall survival, progression-free survival and toxicity
Awards & Highlights
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.
Trial Design
1Treatment groups
Experimental Treatment
Group I: 12 Gy in 6 daily fractionsExperimental Treatment1 Intervention
Find a Location
Who is running the clinical trial?
Sunnybrook Health Sciences CentreLead Sponsor
681 Previous Clinical Trials
1,565,731 Total Patients Enrolled
May Tsao, MDPrincipal InvestigatorSunnybrook Health Sciences Centre
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- My lymphoma is low grade, stages I-IV, and has not been treated with radiation.I am 18 years old or older.My cancer targets are smaller than 7cm.My doctor expects I have less than 3 months to live.My lymphoma is low grade according to Sunnybrook's pathology review.I am not pregnant.I haven't had systemic therapy for lymphoma around my radiotherapy time.I need radiation therapy for my cancer.
Research Study Groups:
This trial has the following groups:- Group 1: 12 Gy in 6 daily fractions
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.