VX-548 for Peripheral Neuropathy
Recruiting in Palo Alto (17 mi)
+49 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Phase 2
Waitlist Available
Sponsor: Vertex Pharmaceuticals Incorporated
No Placebo Group
Prior Safety Data
Trial Summary
What is the purpose of this trial?This trial is testing a medication called VX-548 to see if it can help reduce pain in people with diabetic nerve pain. The medication works by blocking pain signals from traveling through the nerves.
Eligibility Criteria
Inclusion Criteria
You have been diagnosed with type 1 or type 2 diabetes.
Your HbA1c level is less than or equal to 9%.
It seems like there might be a typo or incomplete information. Can you provide more details or clarify the criterion you'd like me to summarize?
+3 more
Exclusion Criteria
You have nerve pain that is not caused by diabetic peripheral neuropathy.
You have a history of heart rhythm problems that needed medication to treat.
You had a heart attack or stroke in the last year.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: VX-548Experimental Treatment3 Interventions
Participants will be randomized to receive different dose levels of VX-548.
Group II: PregabalinActive Control2 Interventions
Participants will receive pregabalin.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Synexus Clinical Research- New YorkNew York, NY
Synexus Clinical Research- AndersonAnderson, SC
Velocity Clinical Research - ClevelandCleveland, OH
Inquest Clinical ResearchBaytown, TX
More Trial Locations
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Who Is Running the Clinical Trial?
Vertex Pharmaceuticals IncorporatedLead Sponsor