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Anti-mitotic Agent

licorice root extract and docetaxel for Prostate Cancer

Phase 2
Waitlist Available
Led By Robert S. DiPaola, MD
Research Sponsored by Rutgers, The State University of New Jersey
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 9 months
Awards & highlights

Summary

RATIONALE: Licorice root extract contains ingredients that may slow the growth of tumor cells. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving licorice root extract together with docetaxel may be an effective treatment for prostate cancer. PURPOSE: This phase II trial is studying the side effects and how well giving licorice root extract together with docetaxel works in treating patients with metastatic prostate cancer that did not respond to hormone therapy.

Eligible Conditions
  • Prostate Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~9 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 9 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percentage of Patients With PSA Response

Trial Design

1Treatment groups
Experimental Treatment
Group I: licorice root extract and docetaxelExperimental Treatment2 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Docetaxel
FDA approved

Find a Location

Who is running the clinical trial?

National Cancer Institute (NCI)NIH
13,841 Previous Clinical Trials
41,002,879 Total Patients Enrolled
566 Trials studying Prostate Cancer
529,799 Patients Enrolled for Prostate Cancer
Rutgers, The State University of New JerseyLead Sponsor
440 Previous Clinical Trials
65,372 Total Patients Enrolled
13 Trials studying Prostate Cancer
1,034 Patients Enrolled for Prostate Cancer
Robert S. DiPaola, MDPrincipal InvestigatorRutgers Cancer Institute of New Jersey
4 Previous Clinical Trials
72 Total Patients Enrolled
4 Trials studying Prostate Cancer
72 Patients Enrolled for Prostate Cancer
~1 spots leftby Sep 2025
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