← Back to Search

Behavioural Intervention

SAS20 for Spinal Cord Injury

Phase 2
Waitlist Available
Research Sponsored by Kathleen Friel
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, immediately after intervention
Awards & highlights

Summary

The purpose of this study is to determine if spinal excitability is increased with a Spinal Associative Stimulation (SAS) protocol, and to determine the functional consequences of this technique on motor recovery.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, immediately after intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, immediately after intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in H-Reflex Threshold
Secondary study objectives
10 Meter Walk Test
Anklebot
Lower Extremity
+3 more

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: SAS20Experimental Treatment1 Intervention
The paired stimulation (SAS) will be comprised of patient adjusted subthreshold TMS (80% of resting motor threshold over optimal site for soleus muscle), delivered 20ms prior to a peripheral nerve stimulus in the popliteal fossa and will be repeated at 0.1 Hz for 15 minutes (90 stimuli pairs).
Group II: SAS0Active Control1 Intervention
The paired stimulation (SAS) will be comprised of patient adjusted subthreshold TMS (80% of resting motor threshold over optimal site for soleus muscle), delivered 0ms prior to a peripheral nerve stimulus in the popliteal fossa and will be repeated at 0.1 Hz for 15 minutes (90 stimuli pairs).
Group III: SAS50Active Control1 Intervention
The paired stimulation (SAS) will be comprised of patient adjusted subthreshold TMS (80% of resting motor threshold over optimal site for soleus muscle), delivered 50ms prior to a peripheral nerve stimulus in the popliteal fossa and will be repeated at 0.1 Hz for 15 minutes (90 stimuli pairs).

Find a Location

Who is running the clinical trial?

Kathleen FrielLead Sponsor
1 Previous Clinical Trials
40 Total Patients Enrolled
Burke Medical Research InstituteOTHER
23 Previous Clinical Trials
1,435 Total Patients Enrolled
Kathleen Friel, PhDStudy DirectorBurke Medical Research Institute
4 Previous Clinical Trials
122 Total Patients Enrolled
~2 spots leftby Sep 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top