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Thyroid lobectomy for Thyroid Cancer

Phase 2
Waitlist Available
Led By Linwah Yip, MD
Research Sponsored by University of Pittsburgh
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

Study Summary

This trial will use ThyroSeq to guide how much of the thyroid is removed during surgery for cancer. Data will be collected on how well this works.

Eligible Conditions
  • Thyroid Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of patients who require completion thyroidectomy for aggressive histology features
Secondary outcome measures
Number of patients who had central compartment neck dissection but no lymph node metastasis were identified
Number of patients with operative complications
QOL metric - FACT-G cumulative score preop, postop, and at followup
+3 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Low RiskExperimental Treatment1 Intervention
Molecular testing and ultrasound features will be used to predict if thyroid cancer is low risk. Intervention will be to perform thyroid lobectomy.
Group II: High RiskExperimental Treatment1 Intervention
Molecular testing and ultrasound features will be used to predict if thyroid cancer is high risk. Intervention will be to perform more aggressive surgery to include total thyroidectomy with CCND.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Thyroid lobectomy
2017
Completed Phase 2
~100
Total thyroidectomy with CCND
2017
Completed Phase 2
~100

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,731 Previous Clinical Trials
16,307,337 Total Patients Enrolled
Linwah Yip, MDPrincipal Investigator - University of Pittsburgh
UPMC Bedford Memorial, UPMC Horizon-Greenville, UPMC Passavant-McCandless, UPMC Presbyterian, UPMC Shadyside, UPMC St. Margaret
University Of Chicago (Medical School)
Northwestern University Medical Sch (Residency)
~12 spots leftby Jun 2025
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