Brace
Lumbar Brace for Back Pain
This trial is testing if wearing a lumbar brace for a few weeks can help people with low back pain who visit the emergency department. The brace supports the lower back, reducing movement and pain. This may decrease the need for painkillers and improve daily function. Lumbar supports are used in the treatment of low-back pain patients to prevent the onset or recurrence of low-back pain.
Biologic Implant
VIA Disc NP Allograft for Degenerative Disc Disease
This trial tests VIA Disc NP, an injection to repair damaged spinal discs, in adults aged 65+ with back pain not relieved by other treatments. The injection adds material to the damaged discs to improve function and reduce pain.
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Trials for CLBP Patients
Behavioral Intervention
Non-pharmacological Pain Management for Post-Spine Surgery Pain
This trial will compare two ways of managing pain after lumbar spine surgery in the Military Health System. One group will receive the standard care, while the other will get an enriched care pathway with the hope of reducing opioids use.
Cognitive Behavioral Therapy
Cognitive Behavioral Therapy for Back and Neck Pain
This trial tests the GOALS program, which combines various sessions to help Hispanic/Latino people with long-term neck or back pain. The program uses mental and physical exercises to manage pain. It aims to improve daily functioning by changing how patients think about and respond to their pain.
Behavioural Intervention
Sitting Ellipticals for Chronic Lower Back Pain
This trial looks at how non-weightbearing elliptical exercise affects people with chronic lower back pain, to see if it can improve vital signs, pain, disability, mental health, etc.
Chemotherapy
Physical Therapy + Antidepressant for Chronic Lower Back Pain with Depression
This trial will look at how different treatments - antidepressants, physical therapy, or a combination of both - affect pain, ability to function, and depression symptoms in people with chronic low back pain.
Procedure
Spinal Manipulation and Mindfulness-Based Stress Reduction for Chronic Lower Back Pain
This trial will aim to test the effectiveness of mindfulness therapy and spinal manipulation therapy in reducing the need for chronic high-dose opioids by measuring changes in endogenous opioid function.
Trials for Lower Back Pain Patients
Behavioral Intervention
Non-pharmacological Pain Management for Post-Spine Surgery Pain
This trial will compare two ways of managing pain after lumbar spine surgery in the Military Health System. One group will receive the standard care, while the other will get an enriched care pathway with the hope of reducing opioids use.
Behavioral Intervention
Guideline-Based Physical Therapy for Lower Back Pain
This trial will evaluate whether following Physical Therapy Clinical Practice Guidelines can reduce pain, disability, and healthcare utilization for low back pain within the Department of Defense and Veterans Affairs healthcare systems.
Behavioral Intervention
Integrated vs. Coordinated Pain Management for Back Pain
This trial is testing whether an Integrated Care Pathway or a Coordinated Care Pathway is more effective in reducing pain and improving function for people with low back pain.
Behavioral Intervention
Stepped Care Management for Lower Back Pain
This trial will study two possible treatments for chronic low back pain, physical therapy or Move 2 Health. If neither of these treatments work after six weeks, patients will then be randomized to receive either the addition of the other treatment or the MORE Mindfulness intervention.
Trials With No Placebo
Behavioral Intervention
Non-pharmacological Pain Management for Post-Spine Surgery Pain
This trial will compare two ways of managing pain after lumbar spine surgery in the Military Health System. One group will receive the standard care, while the other will get an enriched care pathway with the hope of reducing opioids use.
Behavioral Intervention
Guideline-Based Physical Therapy for Lower Back Pain
This trial will evaluate whether following Physical Therapy Clinical Practice Guidelines can reduce pain, disability, and healthcare utilization for low back pain within the Department of Defense and Veterans Affairs healthcare systems.
Behavioral Intervention
Integrated vs. Coordinated Pain Management for Back Pain
This trial is testing whether an Integrated Care Pathway or a Coordinated Care Pathway is more effective in reducing pain and improving function for people with low back pain.
Behavioral Intervention
Stepped Care Management for Lower Back Pain
This trial will study two possible treatments for chronic low back pain, physical therapy or Move 2 Health. If neither of these treatments work after six weeks, patients will then be randomized to receive either the addition of the other treatment or the MORE Mindfulness intervention.
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Frequently Asked Questions
Introduction to low back pain
What are the top hospitals conducting low back pain research?
When it comes to finding effective treatments for low back pain, several hospitals are leading the way in groundbreaking clinical trials. One such institution is Mayo Clinic in Rochester, renowned for its expertise in medical research. Currently, they have three active trials dedicated to low back pain and have conducted six previous studies dating back to their first recorded trial in 2005. Similarly, the Center for Clinical Research in Winston-Salem has been making significant contributions with three ongoing trials and a total of six completed trials since their initial study on low back pain began in 2007.
Moving westward to Salt Lake City, The University of Utah Healthcare System is actively involved in two clinical trials targeting low back pain while having an impressive track record of five completed studies since embarking on this research endeavor starting from 2011.On another note,Sport and Spine Rehab Clinics located conveniently at Landover stands as one of the emerging players engaging themselves into these types of investigations with around two being done currently; yet they've just commenced their exploration towards understanding this condition recently that dated backs only up until2022.In contrast,the Rockville branch also belonging to Sport and Spine Rehab Clinic plays similar role by investing efforts into improving treatment options through conducting two simultaneous experiments right now further adding onto their commendable count which amounts upto a total three different explorations ever since entering the field during2020.
These esteemed hospitals are committed not only to alleviating the burden of low back pain but also pushing the boundaries of medical knowledge and innovation. By actively participating in clinical trials focused on this common ailment, they strive towards enhancing therapeutic solutions that benefit millions who suffer from chronic discomfort. With each new breakthrough brought forth by these healthcare institutions, there lies hope for improved management strategies that can significantly improve quality of life for those dealing with this prevalent condition globally
Which are the best cities for low back pain clinical trials?
When it comes to low back pain clinical trials, several cities have emerged as leaders in research and innovation. Salt Lake City, Utah is currently conducting 8 active trials focused on interventions like Telehealth Physical Therapy, Physical Therapy, and Mindfulness. Montréal, Quebec follows closely behind with 6 ongoing studies exploring treatments such as Interactive therapy, Manual therapy, and PRP injections. San Diego, California also hosts 6 active trials investigating interventions like the GOALS Intervention and Meditation training. Other cities making significant contributions to low back pain research include Durham in North carolina and Boston in Massachusetts. These cities offer individuals suffering from low back pain access to cutting-edge clinical trials that explore various treatment options for better management of this condition.
Which are the top treatments for low back pain being explored in clinical trials?
Exciting developments are underway in the realm of low back pain treatment, with several promising interventions currently being explored in clinical trials. Leading the charge is intervention, a therapy that has captured attention with two active trials and a total of two all-time low back pain trials since its introduction in 2015. Another contender making waves is VIA Disc NP, which also boasts two active trials and an equal number of all-time low back pain trials since its listing in 2020. Additionally, ED Physical Therapy shows promise as it enters the scene with two ongoing clinical trials for low back pain after being first listed just last year. These innovative treatments offer hope for individuals suffering from this debilitating condition and signify progress on the path toward effective relief options.
What are the most recent clinical trials for low back pain?
Recent clinical trials for low back pain have brought forth promising interventions that offer hope to those suffering from this debilitating condition. One notable study investigated the efficacy of dextrose 50% intravenous solution in alleviating low back pain, reaching phase 3 and becoming available on August 1st, 2023. Additionally, a combination treatment involving ibuprofen and dexamethasone coupled with an educational intervention demonstrated potential benefits for managing low back pain during its phase 4 trial, which became accessible on July 5th, 2023. Another intriguing approach is the primary spine provider model implemented in a phase 4 trial since March14th, 2023. These advancements signify significant progress towards finding effective solutions to alleviate the burden of low back pain among individuals seeking relief.
What low back pain clinical trials were recently completed?
Recent clinical trials have made significant progress in the search for effective treatments for low back pain. In April 2022, Scilex Pharmaceuticals completed a trial investigating SP-103, while Eli Lilly and Company concluded their study on LY3526318 in October 2021. Additionally, in May 2021, another trial by Eli Lilly and Company focused on LY3556050 was finalized. These recent advancements highlight the ongoing efforts to address this prevalent condition and provide hope for individuals suffering from low back pain.