Lidocaine for Spinal Diseases

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 4

Waitlist Available

Sponsor: Dartmouth-Hitchcock Medical Center

No Placebo Group

Prior Safety Data

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine the effect of lidocaine infusion on intraoperative neuromonitoring in patients undergoing spine surgery.

Research Team

Eligibility Criteria

This trial is for patients having elective cervical or thoracolumbar spine surgery with special nerve function monitoring. Participants must understand English to give consent and cannot be pregnant, allergic to lidocaine, planned for breathing tube after surgery, or incarcerated.

Inclusion Criteria

I am having spine surgery with nerve function monitoring.

Exclusion Criteria

I cannot give informed consent in English.

Pregnancy (based on patient report or a positive test on the day of surgery)

Contraindication to lidocaine

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Treatment Details

Interventions

Lidocaine (Local Anesthetic)

Trial OverviewThe study is testing the effects of a drug called Lidocaine when infused during spine surgery. It's compared against a saltwater solution (normal saline). The goal is to see how Lidocaine affects the thresholds of motor evoked potentials - signals related to muscle movements.

Participant Groups

2Treatment groups

Active Control

Placebo Group

Group I: Lidocaine Infusion (Active)Active Control1 Intervention

Lidocaine infusion

Group II: Normal Saline Infusion (Sham)Placebo Group1 Intervention

Normal saline infusion