SAP Block for Postoperative Pain
(Cardiac-SAP Trial)

Recruiting in Palo Alto (17 mi)

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Nova Scotia Health Authority

Trial Summary

What is the purpose of this trial?This trial tests a pain relief method using a local anesthetic injected near the chest muscles for heart surgery patients. It aims to reduce pain by numbing chest nerves, helping patients recover more comfortably.

Eligibility Criteria

Adults over 18 undergoing heart valve replacement/repair or bypass surgery via sternotomy can join. They must not be allergic to ropivacaine, have a BMI over 35, weigh less than 50 kg, use high-dose opioids, need emergency surgery, or have severe liver/kidney disease.

Inclusion Criteria

Adult (aged >18 years) patients at time of screening

Undergoing valvular replacement/repair and/or coronary artery bypass grafting (CABG) via median sternotomy

Exclusion Criteria

An allergy to ropivacaine

You are scheduled to undergo circulatory arrest.

You have a body mass index (BMI) over 35.

+10 more

Participant Groups

The trial is testing if the serratus anterior plane (SAP) block with Ropivacaine reduces pain after heart surgery compared to a saline placebo. Participants are randomly chosen to receive either the drug or placebo for three days post-surgery.

2Treatment groups

Active Control

Placebo Group

Group I: Active serratus anterior plane (SAP) block with Ropivacaine 0.2%Active Control1 Intervention

Group II: Placebo serratus anterior plane (SAP) block with normal salinePlacebo Group1 Intervention

Normal Saline Placebo is already approved in United States, Canada, European Union for the following indications:

🇺🇸 Approved in United States as Normal Saline for: