Autologous Blood Patch for Lung Cancer

Recruiting in Palo Alto (17 mi)

Overseen byChristopher W Seder, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Rush University Medical Center

No Placebo Group

Trial Summary

What is the purpose of this trial?A postoperative autologous blood patch (ABP) intervention trial for patients who underwent lung resection for cancer to examine its effectiveness in preventing a prolonged air leak. AIM 1: To determine the safety and efficacy of autologous blood patch (ABP) as a means to reduce the rate of prolonged air leak (PAL) after lung cancer resection AIM 2: To prospectively examine variation in morbidity and quality of life between patients with and without a PAL

Eligibility Criteria

This trial is for adults over 18 who had lung cancer surgery and have an air leak on the third day after their operation. It's not for those who had more extensive surgeries like pneumonectomy, or women who are pregnant.

Inclusion Criteria

I had surgery to remove part of my lung for suspected lung cancer.

Patients that have reviewed and signed the Informed Consent Form, had an opportunity to ask questions, and consent to have their de-identified data included in the study

I have an air leak from my surgery site on the third day after surgery.

+1 more

Exclusion Criteria

I am currently pregnant.

I am 18 years old or younger.

I have had surgery to remove a lung, part of a lung, chest wall, diaphragm, or had surgery on both sides of my chest.

Participant Groups

The study tests if using a patient's own blood to create a patch (ABP) can prevent leaks in the lungs after cancer surgery. Patients will either get this new treatment or the usual care, and researchers will compare how well each works.

2Treatment groups

Experimental Treatment

Active Control

Group I: Autologous Blood PatchExperimental Treatment1 Intervention

60-120ml of patient's blood will be drawn and inserted into patient's chest tube. A minimum of 60ml of blood is required, with the optimal amount of blood being 120ml.

Group II: Standard of Care (Per physician)Active Control1 Intervention

Chest tube remains intact without blood patch.