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NHS for Biomarkers

N/A
Waitlist Available
Led By Vasanti Malik, ScD
Research Sponsored by Harvard School of Public Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
For the current study, we included participants who provided a blood sample and were previously selected as controls for nested case-control analyses of type 2 diabetes, coronary heart disease, stroke, colon cancer, colon polyps, pancreatic cancer, and breast cancer in the Nurse's Health Study.
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up blood collection cyle 2 (2000-2001)
Awards & highlights

Summary

This study is a secondary analysis of data collected in the Nurses' Health Study (NHS) that will evaluat the association between intake of sugar sweetened beverages (SSB), juice and artificially sweetened beverages in relation to biomarkers of hepatic function, lipid metabolism, inflammation and glycemic control.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~blood collection cyle 2 (2000-2001)
This trial's timeline: 3 weeks for screening, Varies for treatment, and blood collection cyle 2 (2000-2001) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Alanine transaminase
Fetuin-A
Gamma-glutamyl transferase
Secondary study objectives
C-reactive protein (CRP)
Hemoglobin A1c
High-density lipoprotein cholesterol (HDL-C)
+7 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: NHSExperimental Treatment1 Intervention
Least-squares mean (95% CI) concentrations of biomarkers by frequency of sugar sweetened beverage (SSB) intake among participants free of diabetes and cardiovascular disease in the NHS. Least-squares mean (95% CI) concentrations of biomarkers by frequency of artificially sweetened beverage (ASB) intake among participants free of diabetes and cardiovascular disease in the NHS. Least-squares mean (95% CI) concentrations of biomarkers by frequency of fruit juice intake among participants free of diabetes and cardiovascular disease in the NHS.

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Who is running the clinical trial?

Harvard School of Public HealthLead Sponsor
122 Previous Clinical Trials
1,903,713 Total Patients Enrolled
Harvard School of Public Health (HSPH)Lead Sponsor
278 Previous Clinical Trials
14,082,130 Total Patients Enrolled
Vasanti Malik, ScDPrincipal InvestigatorResearch Scientist
~1269 spots leftby Sep 2025
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