← Back to Search

Genetic Counseling Chatbot for Kidney Donors

N/A

Waitlist Available

Led By Elisa J Gordon, PhD, MPH

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Not cognitively impaired

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up post-intervention, up to 5 years

Awards & highlights

No Placebo-Only Group

Summary

This trial will test whether a chatbot can help African American living kidney donors make informed decisions about their health.

Who is the study for?

This trial is for English-speaking adults over 18 who are not cognitively or vision impaired. It's specifically for transplant nephrologists evaluating live kidney donor candidates at the study sites, focusing on African American populations.

What is being tested?

The trial tests a culturally adapted APOL1 genetic testing program with a chatbot named Gia and counseling training for nephrologists. It aims to improve decision-making and satisfaction among African American living kidney donors regarding donation risks.

What are the potential side effects?

Since this intervention involves counseling and education rather than medication, traditional side effects aren't expected. However, there may be emotional or psychological impacts from learning about genetic risks.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am not experiencing any significant memory or thinking problems.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ post-intervention, up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~post-intervention, up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and post-intervention, up to 5 years for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Number and quality of prescribed Post-Test counseling practices

Number and quality of prescribed Pre-Test counseling practices

Secondary study objectives

Acceptability of Intervention Measure (AIM)

Clinical Sustainability Assessment Tool (CSAT)

Feasibility of Intervention Measure (FIM)

+2 more

Other study objectives

Barriers and Facilitators to APOL1 testing Implementation

Genetic variation knowledge assessment index (GKAI)

Health Professionals Beliefs about Race (HPBR) scale

+1 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: Counseling Training ProgramExperimental Treatment1 Intervention

The APOL1 counseling training program is designed for transplant nephrologists who evaluate live kidney donor candidates of African ancestry who are at risk for having APOL1 risk variants and kidney failure post-donation. The training program aims to increase transplant nephrologists' practical knowledge, self-efficacy, and skills in counseling live donor candidates about APOL1 in a culturally competent manner. The program will include training in: current APOL1 data; the value of APOL1 testing and meaning of positive test results for living donor clinical evaluation; risks of having two APOL1 gene variants on the donor's kidney health; how to engage in shared decision making about donation; how to address cultural concerns about genetic testing; and how to protect donor candidates' privacy and confidentiality with APOL1 test results. The APOL1 counseling training program will be delivered by a genetic counselor through webinars and other interactive modalities and last 2-4 hours.

0 / 1Eligibility criteria met