Procedure
LCP Patella Plating System vs Traditional Fixation for Knee Fracture
This trial tests a special device for fixing broken kneecaps in adults aged 18-74. The device holds the broken pieces together securely, which may help them heal better than traditional methods.
Behavioral Intervention
Guilt Reduction vs Cognitive Processing Therapy for PTSD
This trial will compare a brief trauma-related guilt therapy to a longer PTSD therapy to see which is more effective in reducing guilt and symptoms of PTSD and depression in veterans.
Popular Filters
Trials for PTSD Patients
Behavioural Intervention
Working Memory Training for PTSD
This trial aims to see if a training program that improves working memory can also improve the ability to overcome fear in Veterans with PTSD. The study will use advanced analyses to understand how working memory and fear extinction
Psychedelic
Psilocybin for PTSD
This trial aims to test if using psilocybin along with therapy can safely and effectively treat PTSD in U.S. Military Veterans. Psilocybin helps change brain activity, making it easier for veterans to process their trauma during therapy.
Behavioral Intervention
Emotional Resilience Training for Post-Traumatic Stress Disorder
This trial aims to help public safety personnel, like firefighters and police officers, manage stress and prevent trauma-related injuries through a special training program. The program teaches skills to handle emotions and stress, with periodic assessments to track progress. The goal is to improve mental health and resilience for these workers.
Behavioral Intervention
Stellate Ganglion Block + Cognitive Processing Therapy for PTSD
This trial aims to see if injecting a local anesthetic into the neck can help military personnel and veterans with PTSD when combined with standard therapy. The treatment targets the nerves that control stress responses to reduce anxiety symptoms. Participants will receive therapy and be randomly assigned to get the injection at different times. This method has been investigated in previous trials for its potential to reduce PTSD symptoms, showing some promise in symptom reduction.
Trials for Post-Traumatic Stress Disorder Patients
Behavioural Intervention
Working Memory Training for PTSD
This trial aims to see if a training program that improves working memory can also improve the ability to overcome fear in Veterans with PTSD. The study will use advanced analyses to understand how working memory and fear extinction
Psychedelic
Psilocybin for PTSD
This trial aims to test if using psilocybin along with therapy can safely and effectively treat PTSD in U.S. Military Veterans. Psilocybin helps change brain activity, making it easier for veterans to process their trauma during therapy.
Behavioral Intervention
Emotional Resilience Training for Post-Traumatic Stress Disorder
This trial aims to help public safety personnel, like firefighters and police officers, manage stress and prevent trauma-related injuries through a special training program. The program teaches skills to handle emotions and stress, with periodic assessments to track progress. The goal is to improve mental health and resilience for these workers.
Behavioral Intervention
Stellate Ganglion Block + Cognitive Processing Therapy for PTSD
This trial aims to see if injecting a local anesthetic into the neck can help military personnel and veterans with PTSD when combined with standard therapy. The treatment targets the nerves that control stress responses to reduce anxiety symptoms. Participants will receive therapy and be randomly assigned to get the injection at different times. This method has been investigated in previous trials for its potential to reduce PTSD symptoms, showing some promise in symptom reduction.
Phase 3 Trials
Behavioural Intervention
Targeted Oxygen Therapy for Critical Illness from Injuries
This trial will test whether a multimodal educational intervention can help to reduce the use of supplemental oxygen in critically injured patients. Additionally, the trial will evaluate the safety and clinical effectiveness of more targeted oxygen therapy.
Acellular Tissue Matrix
Human Acellular Vessel for Vascular Trauma
This trial tests a special type of blood vessel called a Human Acellular Vessel (HAV) in adults with serious blood vessel injuries below the neck. The HAV is used to replace or bypass damaged vessels, helping restore blood flow. The study will follow patients for several years after the procedure. The Human Acellular Vessel (HAV) is a bioengineered conduit developed by Humacyte, Inc., known for its off-the-shelf availability and resistance to infection, making it ideal for complex revascularization scenarios.
Tranexamic Acid for Spinal Injury
This trial is designed to study whether tranexamic acid can reduce blood loss in patients who have sustained a spine injury requiring surgery. The study will last for two years and will compare outcomes in patients who receive tranexamic acid to those who receive a placebo.
Trials With No Placebo
Behavioural Intervention
Alliance180 Program for Trauma
This trial aims to study how the Alliance180 Program affects the physical and mental well-being of US Veterans, First Responders, and Front Line Healthcare Workers. Participants will complete surveys before and after the program
Behavioral Intervention
Children's Therapy for Emotional and Behavioral Issues
"This trial aims to understand how therapy helps children and adolescents aged 8-15 with anxiety, depression, trauma, or disruptive behavior. They want to know if managing negative emotions plays a role in how
Psychedelic
Psilocybin for PTSD
This trial aims to test if using psilocybin along with therapy can safely and effectively treat PTSD in U.S. Military Veterans. Psilocybin helps change brain activity, making it easier for veterans to process their trauma during therapy.
Behavioral Intervention
Emotional Resilience Training for Post-Traumatic Stress Disorder
This trial aims to help public safety personnel, like firefighters and police officers, manage stress and prevent trauma-related injuries through a special training program. The program teaches skills to handle emotions and stress, with periodic assessments to track progress. The goal is to improve mental health and resilience for these workers.
View More Related Trials
Frequently Asked Questions
Introduction to trauma
What are the top hospitals conducting trauma research?
When it comes to tackling traumatic injuries, top hospitals across the United States are actively engaged in innovative clinical trials. The Ohio State University in Columbus is leading the way with three ongoing trauma trials. While this institution may not have conducted any previous trials specifically focused on trauma, its dedication to advancing knowledge and treatment options for these critical conditions is commendable. Similarly, at the University of Alabama at Birmingham in Birmingham, researchers are currently conducting two active trauma trials as part of their commitment to improving outcomes for patients facing traumatic injuries.
In Nashville, Vanderbilt University Medical Center is making significant strides with two ongoing trauma trials that aim to enhance understanding and interventions for individuals affected by severe accidents or life-threatening events. Meanwhile, The University of Texas Health Science Center at Houston has also dedicated its resources to studying traumatic injuries through two active clinical trials aimed at uncovering new approaches and therapies.
Last but not least, we turn our attention to the renowned University of Pittsburgh located in Pittsburgh. This esteemed institution is actively involved in two current trauma trials as they strive towards discovering improved treatments and techniques for those who suffer from devastating traumas.
While these hospitals may not have completed any prior clinical trials related specifically to trauma care yet, their commitment and involvement demonstrate a shared determination amongst medical professionals nationwide – pushing boundaries and seeking breakthrough solutions when it comes to treating individuals affected by traumatic incidents. By working together on these studies, they contribute significantly toward advancing knowledge surrounding effective management strategies during such trying times
Which are the best cities for trauma clinical trials?
When it comes to trauma clinical trials, several cities have emerged as key players in advancing research and treatment options. Among these cities are Houston, Texas, with 13 active trials exploring interventions such as MT-3921 and Cold Stored Platelets (CSP). Dallas, Texas follows closely behind with 8 ongoing studies focused on interventions like Active Transcranial direct current stimulation and BI 1358894. Meanwhile, Toronto, Ontario; Miami, Florida; and Philadelphia, Pennsylvania all boast 7 active trials each delving into various treatments ranging from Red Blood Cells Transfusion to Human Acellular Vessel (HAV) implants. These cities provide valuable contributions to the field of trauma clinical trials by paving the way for new therapies and improving outcomes for individuals affected by traumatic injuries.
Which are the top treatments for trauma being explored in clinical trials?
Clinical trials are actively investigating several promising treatments for trauma. Leading the way is ketamine, a drug that has shown potential in managing trauma-related symptoms and reducing the risk of developing post-traumatic stress disorder (PTSD). Another treatment being explored is virtual reality therapy, which aims to recreate traumatic scenarios in a controlled environment to help individuals process their experiences and alleviate distress. Furthermore, researchers are studying eye movement desensitization and reprocessing (EMDR), a psychotherapy technique that involves guided eye movements to assist in processing traumatic memories. Through these innovative approaches, medical professionals strive to provide effective solutions for those impacted by trauma.
What are the most recent clinical trials for trauma?
Exciting advancements in trauma research are being made through recent clinical trials. Among them, a Phase 1 study is investigating the effectiveness of trauma treatment specifically tailored to address the unique needs of patients. Another Phase 4 trial focuses on reactivating mismatch conditions associated with trauma, aiming to enhance recovery outcomes. Additionally, a combined Phase 1 and Phase 2 trial explores the potential benefits of active transcranial direct current stimulation for trauma healing. These studies showcase promising approaches to improving care for individuals affected by traumatic events, offering hope for better outcomes and enhanced quality of life.
What trauma clinical trials were recently completed?
Several recent clinical trials have focused on trauma and its management, shedding light on innovative approaches to treating traumatic injuries. One notable trial was completed by the University of Maryland in March 2022, investigating the effectiveness of a novel intervention for severe head trauma. Additionally, Massachusetts General Hospital concluded a trial in January 2022 that examined the use of advanced imaging techniques in assessing spinal cord injuries. These studies exemplify ongoing efforts to advance trauma care and expand treatment options for individuals affected by traumatic events.