Cognitive Behavioral Therapy for Sickle Cell Disease
(PRESENCE Trial)

Recruiting in Palo Alto (17 mi)

Overseen byAlicia Colvin, PhD

Age: < 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Recruiting

Sponsor: University of Pittsburgh

No Placebo Group

Trial Summary

What is the purpose of this trial?The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.

Eligibility Criteria

This trial is for young people aged 16-30 with Sickle Cell Disease who experience chronic pain or use pain management treatments regularly. They must have a smartphone with internet to participate and be able to provide proof of their diagnosis.

Inclusion Criteria

I have a smartphone with internet.

I am between 16 and 30 years old.

I have been diagnosed with Sickle Cell Disease.

+1 more

Participant Groups

The PRESENCE study tests if digital Cognitive Behavioral Therapy (CBT) can reduce pain, opioid use, and healthcare visits in adolescents and young adults with SCD. It also examines the impact of peer support on engaging patients in this therapy.

3Treatment groups

Experimental Treatment

Active Control

Group I: CBT w/ Health CoachExperimental Treatment1 Intervention

Group will utilize the Presence app to undergo self CBT for EMA, but with addition of peer health coaches.

Group II: CBT w/o Health coach (self-guided)Active Control1 Intervention

Group will utilize the Presence app to undergo self-guided CBT for EMA, but without peer health coaches.

Group III: Usual Care with no access to CBTActive Control1 Intervention

Participants in the UC group will have access to CaRISMA app to complete a daily pain and mood e-diary, daily record of opiate use, and weekly assessment of pain via the Painimation tool. All other care will be at the discretion of their treating provider