← Back to Search

Behavioural Intervention

High-Intensity Exercise for Aphasia

N/A

Waitlist Available

Led By Maria Ivanova, PhD

Research Sponsored by University of California, Berkeley

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Between the ages of 18 and 80

Aphasia following left hemisphere ischemic or hemorrhagic stroke

Timeline

Screening 3 weeks

Treatment Varies

Follow Up after the intervention (3rd week for the control intervention and 9th week for the experimental intervention)

Awards & highlights

No Placebo-Only Group

Summary

This trial wants to see if a high-intensity exercise program can be done by people with post-stroke aphasia. They want to know if stroke survivors with aphasia can do a long exercise program

Who is the study for?

This trial is for individuals aged 18-80 who have had a stroke resulting in aphasia, are at least 6 months post-stroke, spoke English proficiently before the stroke, and have completed at least 8 years of education. They must be able to walk on their own or with a cane and cleared by a doctor for physical exercise. Those with dementia, other neurological illnesses besides stroke, substance abuse issues, significant visual/hearing disabilities, or uncontrolled heart/lung/metabolic conditions cannot participate.

What is being tested?

The study is testing whether people with post-stroke aphasia can stick to an intense workout program and if it helps improve their fitness level as well as cognitive and language abilities. Participants will either do low-intensity exercises (as a control group) or high-intensity workouts (as the target intervention).

What are the potential side effects?

While not explicitly listed in the provided information, potential side effects from participating in physical exercise programs may include muscle soreness, fatigue, joint pain or injury risk; however these depend on individual health status and should be monitored.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18 and 80 years old.

Select...

I have difficulty speaking due to a stroke in the left side of my brain.

Select...

I can walk on my own, but I may use a cane.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ after the intervention (3rd week for the control intervention and 9th week for the experimental intervention)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~after the intervention (3rd week for the control intervention and 9th week for the experimental intervention)

This trial's timeline: 3 weeks for screening, Varies for treatment, and after the intervention (3rd week for the control intervention and 9th week for the experimental intervention) for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change on the Western Aphasia Battery (WAB) - Aphasia Quotient

Secondary study objectives

Attendance

Change in Gait Speed

Change on the 2-minute Step Test

+4 more

Other study objectives

Change on the Curtiss-Yamada Comprehensive Language Evaluation - Revised (CYCLE-R)

Change on the Modified Rankin Scale (MRS)

Change on the Philadelphia Naming Test (PNT)

+6 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: High-intensity physical exerciseExperimental Treatment1 Intervention

The participants will take part in a high-intensity Aphasia Physical EXercise (APEX) intervention designed specifically for individuals with chronic post-stroke aphasia for 8 weeks.

Group II: Low-intensity physical exerciseActive Control1 Intervention

The participants will participate in a low-intensity non-aerobic exercise program for 2 weeks.

0 / 3Eligibility criteria met