Lower Oxygen Concentration for Preventing Collapsed Lung (RESPIRA-EIT Trial)

N/A

Recruiting

Research Sponsored by Beth Israel Deaconess Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

* Elective surgery with general anesthesia and endotracheal intubation

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the cov is measured at six points: pre-induction, post-intubation, pre-washout, pre-extubation, 1 min post-extubation, and 60 min post-extubation in the pacu. the primary outcome is the difference between pre-induction and 1 min post-extubation.

Awards & highlights

No Placebo-Only Group

Summary

This trial aims to study whether using a lower oxygen concentration (70% compared to 100%) before removing a breathing tube reduces the risk of lung tissue collapse (atelectasis) in patients under anesthesia

Who is the study for?

This trial is for adults over 18 who are having elective surgery with general anesthesia and endotracheal intubation, lasting between 1-5 hours. They must consent to participate in the study.

What is being tested?

The study tests if using a lower oxygen concentration (70%) before removing a patient's breathing tube reduces lung collapse compared to the standard high oxygen level (100%). Patients are randomly assigned to one of these two approaches.

What are the potential side effects?

Potential side effects may include difficulty breathing or low blood oxygen levels after extubation. The risk of re-intubation or needing non-invasive ventilation post-surgery might also be affected.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am scheduled for a surgery that requires being put to sleep and a breathing tube.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the length of stay in the pacu is measured in minutes from admission to discharge from the pacu.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the length of stay in the pacu is measured in minutes from admission to discharge from the pacu.

This trial's timeline: 3 weeks for screening, Varies for treatment, and the length of stay in the pacu is measured in minutes from admission to discharge from the pacu. for reporting.