Hydrogen Breathalyzer for Small Intestinal Bacterial Overgrowth
(AIRE Trial)

Recruiting in Palo Alto (17 mi)

Overseen byPankaj Pasricha, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Johns Hopkins University

No Placebo Group

Trial Summary

What is the purpose of this trial?This trial is testing a handheld device called AIRE that measures hydrogen in the breath to diagnose SIBO. It is aimed at patients suspected of having SIBO because current tests are not very accurate and are inconvenient. The device works by detecting hydrogen gas produced by bacteria in the small intestine and provides immediate results through a smartphone app.

Eligibility Criteria

This trial is for adults over 18 with chronic gastrointestinal symptoms like nausea, bloating, or abdominal pain and a clinical diagnosis of SIBO. Participants must be able to eat normally and use a smartphone with Bluetooth. Those on recent antibiotics, with inflammatory bowel disease, or on restrictive diets cannot join.

Inclusion Criteria

Access to a smartphone with Bluetooth capability

I am 18 years old or older.

I have had GI symptoms like nausea or bloating for over 3 months due to scleroderma.

+3 more

Exclusion Criteria

I have a history of inflammatory bowel disease.

I have taken antibiotics in the last 30 days.

You are currently on a special diet, like a low FODMAP diet.

+1 more

Participant Groups

The study tests the AIRE device, a handheld breath analyzer that measures hydrogen in breath to identify food sensitivities related to SIBO. It aims to see if this portable device can more accurately detect SIBO compared to current standard methods.

1Treatment groups

Experimental Treatment

Group I: Breath analyzerExperimental Treatment1 Intervention

Candidates who, after the screening period are eligible to receive the AIRE device.