Hypofractionated Radiotherapy for Endometrial and Cervical Cancers (HERA Trial)

N/A

Recruiting

Led By Puja S. Venkat, MD

Research Sponsored by Jonsson Comprehensive Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Histologically confirmed endometrial or cervical cancer

Surgical resection of the primary tumor

Must not have

Must not meet indications for receiving concurrent chemotherapy as standard of care

History of prior irradiation to the area to be treated

Timeline

Screening 3 weeks

Treatment Varies

Follow Up treatment to 12 weeks after completion of radiotherapy

Awards & highlights

No Placebo-Only Group

Summary

"This trial is testing a new type of radiation therapy called hypo-fractionated radiation therapy for women who have undergone surgery to remove endometrial and/or cervical tumors. The study aims to see if this

Who is the study for?

This trial is for women who have had surgery to remove endometrial or cervical cancer. They should be candidates for post-surgery radiation therapy and able to undergo MRI or CT scans. Specific details about inclusion and exclusion criteria are not provided, but typically participants must meet certain health standards.

What is being tested?

The study tests hypo-fractionated external beam radiotherapy after surgery in women with endometrial or cervical cancers. This approach uses fewer, larger doses of radiation compared to the standard method, aiming to maintain effectiveness while reducing treatment time.

What are the potential side effects?

While specific side effects are not listed, hypo-fractionated radiotherapy may include skin irritation, fatigue, mild swelling at the treatment site, and potential impacts on nearby organs such as the bladder or bowel.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My cancer diagnosis is confirmed for either endometrial or cervical cancer.

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I have had surgery to remove my primary tumor.

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My cancer is in the early to advanced stages but hasn't spread far.

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I am 18 years old or older.

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I can care for myself but may not be able to do active work.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

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I am not required to have chemotherapy as part of my standard treatment.

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I have had radiation therapy to the area that needs treatment now.

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I am currently being treated for another cancer.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks after completion of radiotherapy until 5 years after completion of radiotherapy

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks after completion of radiotherapy until 5 years after completion of radiotherapy

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks after completion of radiotherapy until 5 years after completion of radiotherapy for reporting.