Neurofeedback for Mild Cognitive Impairment

Recruiting in Palo Alto (17 mi)

Overseen byMarian Luctkar-Flude, PhD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: Kingston Health Sciences Centre

No Placebo Group

Trial Summary

What is the purpose of this trial?

The goal of this pilot study is to determine the feasibility, acceptability and potential impact of using neurofeedback interventions to manage cognitive, emotional, and behavioural symptoms in individuals with mild cognitive impairment (MCI). The main question\[s\] it aims to answer are: (1) What is the feasibility, acceptability, and appropriateness of using the Nonlinear Dynamical Neurofeedback intervention for persons living with MCI? (2) What is the feasibility, acceptability, and appropriateness of using the Low Energy Neurofeedback System (LENS) intervention for persons living with MCI? (3) What is the feasibility, acceptability, and appropriateness of using the Brain Music neurofeedback intervention for persons living with MCI? (4) What is the potential impact of five weeks of a neurofeedback intervention on cognitive, affective, and behavioural symptoms experienced by persons living with MCI? Participants will be randomly assigned to either the Nonlinear Dynamical (NLD), Low Energy Neurofeedback System (LENS), or Brain Music neurofeedback intervention groups or a control group receiving usual care.

Research Team

Marian Luctkar-Flude, PhD

Principal Investigator

Queen's University, School of Nursing

Eligibility Criteria

This trial is for individuals with Mild Cognitive Impairment (MCI). Participants should be willing to undergo neurofeedback interventions or receive usual care. Specific inclusion and exclusion criteria details are not provided.

Inclusion Criteria

I have mild memory problems and am seeing a doctor at Providence Care Hospital.

Exclusion Criteria

I have cognitive issues due to a psychiatric condition.

I have cognitive issues due to a recent brain injury.

Treatment Details

Interventions

Brain Music (Behavioural Intervention)
Low Energy Neurofeedback System (Behavioural Intervention)
Nonlinear Dynamical Neurofeedback (Behavioural Intervention)

Trial OverviewThe study tests the feasibility, acceptability, and impact of three neurofeedback techniques—Nonlinear Dynamical Neurofeedback (NLD), Low Energy Neurofeedback System (LENS), and Brain Music—compared to usual care in managing MCI symptoms.

Participant Groups

4Treatment groups

Experimental Treatment

Group I: Usual CareExperimental Treatment1 Intervention

The Usual Care control group will continue to be followed in the Memory clinic at intervals determined by their clinician. Participants will complete the pretest and post-test assessments and surveys at baseline and at the end of 5 weeks.

Group II: Nonlinear dynamical neurofeedback (NLD)Experimental Treatment1 Intervention

The NLD study intervention will consist of 10 sessions of NeurOptimal neurofeedback delivered twice a week over a 5-week period. The intervention will be delivered by a certified NeurOptimal trainer. The average session length is 45 minutes including setup. Additional time of 15-20 minutes will be required prior to sessions when the surveys are completed.

Group III: Low energy neurofeedback system (LENS)Experimental Treatment1 Intervention

The LENS study intervention will consist of 5 sessions of LENS neurofeedback delivered by a certified LENS trainer once a week over a 5-week period. The average session length is 15 minutes including setup. Additional time of 15-20 minutes will be required prior to sessions when the surveys are completed.

Group IV: Brain MusicExperimental Treatment1 Intervention

The Brain Music study intervention will consist of a brain mapping data acquisition session to create the personalized music, followed by 5 weekly sessions to adjust the music that participants will listen to at home on a daily basis. Initial data acquisition and weekly sessions will take about 30 minutes. Additional time of 15-20 minutes will be required prior to sessions when the surveys are completed.