Trial Summary
What is the purpose of this trial?To determine the efficacy of a cognitively enhanced exercise intervention - Tai Ji Quan: Moving to Maintain Brain Health in improving global cognitive function and dual-task ability in older adults with mild cognitive impairment.
Eligibility Criteria
This trial is for older adults with mild cognitive impairment who can safely exercise and have a CDR score ≤0.5 and MMSE ≥24, indicating normal general cognitive function. They must be willing to follow the study's protocol for 24 weeks plus a 6-month follow-up but not already engaged in Tai Ji Quan or similar vigorous physical activities.Inclusion Criteria
Clinical dementia rating (CDR) scale score ≤0.5
Having normal general cognitive function screened, with MMSE ≥24
My doctor says I can safely exercise.
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Exclusion Criteria
I do not have any health conditions like severe heart failure or cancer spread that would limit my physical activity or survival.
You have been doing intense physical activities like Tai Ji Quan, brisk walking for 30 minutes or more at a time, or weight lifting on 3 or more days per week for the past 3 months.
Participant Groups
The trial tests 'Tai Ji Quan: Moving to Maintain Brain Health,' an exercise program designed to improve overall brain function and the ability to do two things at once (dual-task ability) in older adults with mild cognitive issues.
3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Cognitively enhanced Tai Ji QuanExperimental Treatment1 Intervention
Participants in this arm will exercise a series of Tai Ji Quan-based movements with configurations that are specifically designed for older adults to improve cognitive function, dual-task ability, strength/balance, and mobility.
Group II: Standard Tai Ji QuanActive Control1 Intervention
Serving as an active comparison arm, participants in this intervention will exercise a series of Tai Ji Quan-based movements that are specifically designed for older adults to improve strength/balance, cognitive function, and mobility.
Group III: StretchingPlacebo Group1 Intervention
Serving as a control arm, participants in this intervention will engage in a series of light exercise activities consisting of breathing, stretching, and body relaxation.
Find a Clinic Near You
Research Locations NearbySelect from list below to view details:
Oregon Research InstituteEugene, OR
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Who Is Running the Clinical Trial?
Oregon Research InstituteLead Sponsor