← Back to Search

Tai Ji Quan for Mild Cognitive Impairment

N/A

Waitlist Available

Led By Fuzhong Li, Ph.D.

Research Sponsored by Oregon Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 65 years old

Must not have

Having medical conditions likely to compromise survival, such as metastatic cancer, or render a participant unable to engage in physical activity, such as severe cardiac failure

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 6 months

Summary

This trial will test whether a cognitively enhanced exercise intervention can improve global cognitive function and dual-task ability in older adults with mild cognitive impairment.

Who is the study for?

This trial is for older adults with mild cognitive impairment who can safely exercise and have a CDR score ≤0.5 and MMSE ≥24, indicating normal general cognitive function. They must be willing to follow the study's protocol for 24 weeks plus a 6-month follow-up but not already engaged in Tai Ji Quan or similar vigorous physical activities.

What is being tested?

The trial tests 'Tai Ji Quan: Moving to Maintain Brain Health,' an exercise program designed to improve overall brain function and the ability to do two things at once (dual-task ability) in older adults with mild cognitive issues.

What are the potential side effects?

Since this intervention involves physical activity, potential side effects may include typical exercise-related risks such as muscle soreness, fatigue, or falls. However, participants are screened beforehand to ensure they can exercise safely.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:

Select...

I do not have any health conditions like severe heart failure or cancer spread that would limit my physical activity or survival.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 6 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Montreal Cognitive Assessment

gait under a dual-task condition - walking with no cognitive task, walking with a concurrent cognitive task

Secondary study objectives

Clinical Dementia Rating

Computerized cognitive battery tests

Paper-and-pencil domain-specific cognitive battery tests

+1 more

Other study objectives

Activity and movement confidence scales

Depression - Geriatric Depression Scale (GDS)

Physical activity - International Physical Activity Questionnaire (IPAQ)

+2 more

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Cognitively enhanced Tai Ji QuanExperimental Treatment1 Intervention

Participants in this arm will exercise a series of Tai Ji Quan-based movements with configurations that are specifically designed for older adults to improve cognitive function, dual-task ability, strength/balance, and mobility.

Group II: Standard Tai Ji QuanActive Control1 Intervention

Serving as an active comparison arm, participants in this intervention will exercise a series of Tai Ji Quan-based movements that are specifically designed for older adults to improve strength/balance, cognitive function, and mobility.

Group III: StretchingPlacebo Group1 Intervention

Serving as a control arm, participants in this intervention will engage in a series of light exercise activities consisting of breathing, stretching, and body relaxation.

0 / 1Eligibility criteria met