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Resistance Exercise + Creatine for Colorectal Cancer

N/A
Recruiting
Led By Ciaran Fairman, PhD
Research Sponsored by University of South Carolina
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Must not have
Individuals receiving active treatment for their cancer
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10-weeks
Awards & highlights

Summary

"This trial aims to study the effects of combining creatine supplementation with resistance training in colorectal cancer survivors who are experiencing muscle mass and function decline. The study will compare the effectiveness of a 10-week

Who is the study for?
This trial is for colorectal cancer survivors who have sarcopenia, a condition involving loss of muscle mass and function. Participants should be interested in a 10-week program that includes resistance exercise with or without creatine supplementation.
What is being tested?
The study compares two groups: one doing resistance exercises while taking creatine (EXSUPP) and the other doing just the exercises (EXPLA). The goal is to see if adding creatine improves muscle health after cancer treatment.
What are the potential side effects?
Creatine is generally safe but can sometimes cause weight gain due to water retention, digestive issues like nausea or diarrhea, and muscle cramping. Resistance exercise is typically well-tolerated but may lead to muscle soreness.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I am currently undergoing treatment for my cancer.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10-weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 10-weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Exercise Adherence
Recruitment
Retention
+1 more
Secondary outcome measures
Body Composition
Handgrip Strength
Health-Related Quality of Life
+5 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Exercise + CreatineExperimental Treatment1 Intervention
3 days a week of resistance exercise for 10-weeks + 5g day of creatine monohydrate supplementation
Group II: Exercise + PlaceboPlacebo Group1 Intervention
3 days a week of resistance exercise for 10-weeks + 5g day of placebo (dextrose supplementation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Resistance Exercise
2017
Completed Phase 4
~880

Find a Location

Who is running the clinical trial?

University of South CarolinaLead Sponsor
217 Previous Clinical Trials
121,325 Total Patients Enrolled
Ciaran Fairman, PhDPrincipal InvestigatorUniversity of South Carolina
~22 spots leftby Jul 2025
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